We present the design and implementation of a state-of-polarization (SOP) management technique and two efficient synchronizing methods for quantum key distribution (QKD) systems. This is achieved following a wavelength-division multiplexing approach, where the classical synchronization signal and the quantum states are propagated in the same optical fiber. The employed frame synchronization method is based on the monitoring of the quantum bit error ratio (QBER) of the quantum channel, thus avoiding additional hardware and high computational resources. We evaluate the operation of SOP generation method through the assessment of the individual response of the waveplates that comprise the employed electronic polarization controller. Finally, the performance was assessed by computing the overall QBER and the QBER contributions of each of the four polarization states associated with the different qubits. The measurements, obtained during six hours, show a slight variation of the QBER values associated with the individual contributions, reaching an overall QBER of 0.75%. This demonstrates the capability of the presented methods to operate, stably, with very low QBER values, making its application in practical QKD systems reliable.