Sedative Effects of Medetomidine in Pigeons (Columba livia)

Dexmedetomidine chemical restraint of two raptor species undergoing inhalation anaesthesia

“…Such an unpredicted effect in birds diverges from that reported in the literature for other alpha 2-agonist drugs, particularly for Medetomidine (Sandmeier 2000;Paul-Murphy and Fialkowski 2001;Pollock et al 2001;Gunkel and Lafortune 2005).…”

Medetomidine elicit variable effects on sedative indices, hematological and physiological parameters in domestic pigeons (Columba livia)

“…The same effect was reported by Onifade and Ismaila (2009) using detomidine in pigeons; but a dose dependent effect on duration of action was observed using the drug. Other researchers also reported a dosedependent duration of action in pigeons (Pollock et al, 2001; and other domestic animals (Vanio and Palmu, 1989;Onifade, 2007). Alpha-2-agonist was known for its longer dose-dependent duration of effect.…”

“…Tel: +60169647234 or +234 8065280614. agents in birds is associated with a lot of cardiopulmonary complications. Studies and clinical applications of medetomidine in pigeons examine its application as an inductive agent or a free anesthetic agent in combination with other drugs like ketamine and midazolam (Pollock et al, 2001;Lumeij and Deenik 2003;. Previous studies reported elevation in blood pressure, decrease in heart rate, hypoventilation, hypoxemia and hypercapnia when xylazine and ketamine combination is used in different avian species (Raffe et al, 1993;Lumeij and Deenik 2003).…”

Galliformes and Columbiformes

“…In pigeons, xylazine (16 mg/kg IM) or detomidine (1.4 mg/kg IM) produced only minor to moderate sedation adequate for handling and sample collection (Durrani et al 2008(Durrani et al , 2009. Similarly, in pigeons, medetomidine (0.08-2.0 mg/kg IM) produced inadequate sedation for handling and minor diagnostic procedures accompanied by moderate bradypnea and bradycardia (Pollock et al 2001;Sandmeier 2000). At the lower end of the dosage range, it only produced ataxia to sternal recumbency with retention of the righting reflex (Pollock et al 2001).…”

“…Similarly, in pigeons, medetomidine (0.08-2.0 mg/kg IM) produced inadequate sedation for handling and minor diagnostic procedures accompanied by moderate bradypnea and bradycardia (Pollock et al 2001;Sandmeier 2000). At the lower end of the dosage range, it only produced ataxia to sternal recumbency with retention of the righting reflex (Pollock et al 2001). In chickens, and presumably other birds, xylazine inhibits ventricular activity (Park & Park 1988).…”