The modern age is one of international integration and intercultural exchange. The speed and ease with which individuals can share information internationally means almost any discussion can move from the local to the global instantly (Collins, 2010). Local interactions can thus have global consequences individual actors might never fully realize (Kleineberg & Boguña´, 2016). At the same time, trends in international migration and global employment mean communities increasingly encompass individuals from varying cultural and linguistic backgrounds (Milanovic, 2013). Such factors have important implications for communicating about medicine, health, and care on global and local levels. The ease with which humans can travel internationally means infections can spread rapidly across the globe (Tatem, Rogers, & Hay, 2006). This situation also means addressing disease outbreaks and treating afflicted populations requires a global perspective (World Health Organization, 2018). As a result, health organizations around the world increasingly exchange information to address local health situations (Evans, 2016). In this way, public health has become a matter of global interaction and exchange. In these situations, effective cross-cultural communication is essential to success (Rajiv, Rimal, & Lapinski, 2009). Yet engaging in such exchanges is not easy, for the contexts in which they occur are often complex. Successful interactions in these situations involve integrating concepts from health, medical, and care communication with ideas from international and cross-cultural communication.