Segmental and nonsegmental childhood vitiligo has distinct clinical characteristics: A prospective observational study

Mazereeuw‐Hautier, J.; Bezio, Sophie; Mahé, E.; Bodemer, Christine; Eschard, C.; Viseux, V.; Labrèze, Christine; Plantin, P.; Barbarot, S.; Vabres, P.; Martin, Ludovic; Paul, C.; Lacour, Jean‐Philippe

doi:10.1016/j.jaad.2009.06.081

Cited by 77 publications

(73 citation statements)

References 18 publications

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“…The exact reasons for this are unclear. Our review show a preponderance of girls in children with vitiligo, similar to the observation made in majority of previously reported studies [6][7][8][9]10]. Although, two studies from Korea and China noted an almost equal incidence in boys and girls [2,11,12].…”

Section: Discussionsupporting

confidence: 91%

“…In individuals with fair skin, vitiligo is usually visible after a first sun exposure that will accentuate the contrast with healthy skin. a predominance of girls is noted in all pediatric series [3,[5][6][7]. If all races can be affected, it would seem that the prevalence of child vitiligo is higher in India, but it could be secondary to increased social attention [8].…”

Section: Introductionmentioning

confidence: 99%

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Childhood vitiligo: Clinical epidemiological profile

Lahlou¹,

Baybay²,

Gallouj³

et al. 2017

Our Dermatol Online

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Childhood vitiligo: Clinical epidemiological profile

Lahlou¹,

Baybay²,

Gallouj³

et al. 2017

Our Dermatol Online

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“…Furthermore upregulation of, as well as increase in, Nerve Growth Factor (NGF) has been noted in psoriatic plaques by some authors [5]. This could, nonetheless, be a conclusion that may not be subject to generalisation, as, in contrast to psoriasis, vitiligo appears to show a higher frequency of the Koebner phenomenon in nonsegmental (47.19%), vs. segmental vitiligo (24.00%), which is hypothesised by some as having a neural aetiology [6]. Pharmacologic inhibition of epidermal growth factor receptor (EGFR) by EGFR inhibitors leading to enhanced and protracted inflammation in the skin is also a putative mechanism of production of the Koebner effect [7].…”

Section: Discussionmentioning

confidence: 99%

Does pityriasis rosea Koebnerise?

Nwabudike¹

2013

Our Dermatol Online

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The Koebner phenomenon or isomorphic phenomenon is described in dermatology texts as the production of lesions of the original disease, in clinically uninvolved skin, following trauma. The lesions are located at the site of trauma and evidence of a traumatic causation is the linear arrangement of some of the lesions, such as in the case of lichen planus. Other disorders known to exhibit the Koebner phenomenon include psoriasis and vitiligo. A number of other diseases are associated with the Koebner phenomenon. Pathergy is a phenomenon of pustule production following trauma, which occurs in certain disorders such as Pyoderma gangrenosum and Behçet's disease. In some disorders such as impetigo and verruca vulgaris, inoculation may give the appearance of the Koebner phenomenon. A case of pityriasis rosea and Koebner phenomenon at the site of routine blood assay is described in this work. This author has not thus far encountered any description of the Koebner reaction in relation to pityriasis rosea in the literature, but, perhaps, with this report, other physicians will be more open to this possibility and actually uncover similar cases.

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“…although both genetic [7] and environmental factors are the ones implicated as the major cause [8], however, there are other several factors proposed in the pathogenesis of the disease (Figure 1), these include the following, physical trauma [9,10], psychological stress [11], infections [12], neural factors [11,13,14], biochemical factors [15][16][17], melanocytes growth factors [18], melanocortin hormones [19] and autoimmunity [20].…”

Section: Introductionmentioning

confidence: 99%

Autoantibodies Profile in Vitiligo

Hamid¹,

Bitsue²,

Mirshafiey³

2015

Pigmentary Disorders

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Vitiligo is one of the disease which is yet to understand its pathogenesis, however many studies associate this disease as an autoimmune. Detection of autoimmune cells in the serum, lesional and perilesional area of vitiligo patients gives more insight on the disease mechanism. Presence of autoantibodies against melanocytes antigens in vitiligo patients indicates an autoimmune involvement in the aetiology of the disease. Identification and characterization of vitiligo autoantibodies would pave the way for developing new laboratory test for diagnosis. Studying the autoantibodies profile can give an impression on the disease condition of vitiligo patients. We realized the need of research emphasis in this area as more is yet to be discovered. In this review we give an account on different autoantibodies and their associated autoantigens in vitiligo as another effort of providing an updated data for detail analysis.

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Segmental and nonsegmental childhood vitiligo has distinct clinical characteristics: A prospective observational study

Cited by 77 publications

References 18 publications

Childhood vitiligo: Clinical epidemiological profile

Childhood vitiligo: Clinical epidemiological profile

Does pityriasis rosea Koebnerise?

Autoantibodies Profile in Vitiligo

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