Segmental arterial mediolysis: course, sequelae, prognosis, and pathologic–radiologic correlation

Slavin, Richard E.

doi:10.1016/j.carpath.2008.09.001

Cited by 137 publications

(221 citation statements)

References 18 publications

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“…The abdominal visceral arteries are most frequently involved, but any vessel may be affected, including the retroperitoneal, renal, intracranial, and coronary arteries. Cardiac vessel involvement is more frequent in utero and in neonates and young adults; basal cerebral artery involvement is also more frequent in young adults (5).…”

Section: What Is Sam?mentioning

confidence: 99%

A Patient with Acute Kidney Pain and High Blood Pressure

Cohen

Soulen

2015

Clinical Journal of the American Society of Nephrology

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This case presented challenging diagnostic and management issues in a young healthy man who presented with abdominal pain and new-onset hypertension. The differential diagnosis evolved over the course of the clinical presentation. The patient had severe vascular involvement of his renal and basal cerebral arteries that initially was assumed to be due to a vasculitic process or hypercoagulable state. Finally it became apparent that the patient did not have a systemic illness but rather a localized vascular disease most likely due to segmental arterial mediolysis, a rare, under-recognized condition that can potentially be fatal. This condition is often difficult to distinguish from fibromuscular dysplasia. It is important to recognize and correctly diagnose the condition, particularly in the acute phase of the disease, because delay in diagnosis can contribute to morbidity and mortality.

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Section: What Is Sam?mentioning

confidence: 99%

A Patient with Acute Kidney Pain and High Blood Pressure

Cohen

Soulen

2015

Clinical Journal of the American Society of Nephrology

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“…Although SAM is not a systemic disease, two or more arterial segments, i.e., most frequently abdominal arteries and the branches of the celiac axis, may be affected (8). In our case, two different CTAs performed over 1 month showed the aneurysms of multiple abdominal arteries.…”

Section: Discussionmentioning

confidence: 55%

“…Typical lesions of SAM occur in a skip pattern within the large abdominal arteries (8). The most common radiological findings are aneurysms, arterial dilatation at acute onset, and occlusions, while dissections and stenotic lesions were observed in delayed cases.…”

Section: Discussionmentioning

confidence: 99%

Segmental arterial mediolysis mimics systemic vasculitis

et al. 2016

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Segmental arterial mediolysis (SAM) is a rare, nonarteriosclerotic, noninflammatory vascular disease and mostly affects medium-to-large sized abdominal arteries as well as presents with hemorrhages in the abdominal cavity. We report the case of a patient with SAM of the celiac, right renal, jejunal branch of the superior mesenteric, left gastric, and splenic arteries who was diagnosed by excluding other causes and in whom transcatheter embolization was performed in two different sessions, but he died because of an undefined reason. SAM mimics systemic vasculitis and causes abdominal pain; it should be considered because abdominal hemorrhage or arterial infarction can result in death.

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“…[3][4][5] Thirty-three percent to 44% of patients with SAM have multiple SAAs. 5,6) In addition, the angiographic findings of some patients show the presence of bead-like appearance other than aneurysms.…”

mentioning

confidence: 99%

“…5,6) In addition, the angiographic findings of some patients show the presence of bead-like appearance other than aneurysms. Although histological examination is the gold standard for the diagnosis of SAM, 4) and the criteria for the clinical diagnosis of SAM are yet to be established, radiological findings sometimes contribute to the clinical diagnosis of SAM after excluding other suspected systemic diseases. [6][7][8][9] Herein, we report the case of a patient who had multiple SAAs without any atherosclerotic, inflammatory, or hereditary causes; one of the SAAs showed intra-abdominal hemorrhage.…”

mentioning

confidence: 99%

Acute Remodeling of an Adjoining Aneurysm after Endovascular Treatment of a Ruptured Splanchnic Arterial Aneurysm: A Case of Clinically Diagnosed Segmental Arterial Mediolysis

Nishikawa

Hoshina

Sasaki

et al. 2012

Annals of Vascular Diseases

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A 61-year-old woman with multiple splanchnic arterial aneurysms (SAAs) was transferred to our hospital in a state of shock. She underwent coil embolization under the diagnosis of ruptured pancreaticoduodenal artery aneurysm. Follow-up computed tomography performed 2 weeks later showed rapid enlargement of a gastric artery aneurysm, and she underwent an additional embolization. Atherosclerotic, inflammatory or hereditary causes were excluded, and the patient was clinically diagnosed with segmental arterial mediolysis accompanied by multiple SAAs, one of which showed acute remodeling after endovascular treatment.

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Segmental arterial mediolysis: course, sequelae, prognosis, and pathologic–radiologic correlation

Cited by 137 publications

References 18 publications

A Patient with Acute Kidney Pain and High Blood Pressure

A Patient with Acute Kidney Pain and High Blood Pressure

Segmental arterial mediolysis mimics systemic vasculitis

Acute Remodeling of an Adjoining Aneurysm after Endovascular Treatment of a Ruptured Splanchnic Arterial Aneurysm: A Case of Clinically Diagnosed Segmental Arterial Mediolysis

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