Segmental bioelectrical impedance analysis for Korean older population with cold pattern

Abstract

ObjectiveThis study examined the association of whole-body composition and segmental bioimpedance variables with cold pattern (CP) in different sexes.MethodsWe assigned 667 older individuals to a CP group (n = 488) and a non-CP group (n = 179) by using an eight-item self-administered questionnaire. Seven body composition variables and three pairs of segmental bioimpedance variables for the upper and lower extremities, which were obtained from a segmental multifrequency bioimpedance analyzer, were employed to investigate their association with CP. Participants’ characteristics were first described. Then we compared the selected body composition and bioimpedance variables between the CP and non-CP groups. Finally, their association with CP was investigated using univariate and multivariate regression analyses. All analyses were performed separately for women and men.ResultsBoth women and men exhibited a comparable mean age in the CP and non-CP groups; however, women with CP had significantly lower blood pressures, whereas men with CP showed a higher proportion of osteoarthritis than those without CP. Compared with the non-CP group, individuals with CP exhibited significantly smaller body sizes indicated by shorter height and smaller weight, lower body mass index, and smaller volume-to-body surface area ratio in both sexes. After controlling for age, height, weight, and other covariates, we found significant reductions in body lean mass such as fat-free mass and body cell mass, basal metabolic rate per unit mass, total body water, and intra-to-extracellular water ratio in the CP group. With regard to segmental bioimpedance analysis, the resistance ratios and phase angles in the upper and lower extremities yield significant associations with CP incidence, as demonstrated by the odds ratio (95% confidence interval) of 1.72 (1.16–2.57), 1.69 (1.18–2.48), 0.60 (0.40–0.89), and 0.57 (0.39–0.82), respectively. However, these results did not emerge in men.ConclusionAbnormal cellular water distribution and deterioration in body cell mass and/or cell strength are associated with CP prevalence, regardless of age, height, weight. These findings are similar in the upper and lower extremities and are more pronounced in women. The abovementioned patterns may be considered effective indicators for identifying CP in the older adult population.

A screening method for mild cognitive impairment in elderly individuals combining bioimpedance and MMSE

“…Previous studies have shown differences in BIA variables between individuals with diabetes and those without, particularly in PhA (Jun et al, 2018). Considering the previous research findings (Doan et al, 2022a(Doan et al, ,b, 2023, differences in BIA variables between MCI and normal groups persist even after adjusting for conditions like hyperlipidemia, diabetes, and CNS disorders. In our study, there was a difference in diabetes prevalence between the MCI and NC groups in the male group, but no significant difference was observed in the female group.…”

“…On the other hand, BIA variables are influenced by factors such as sex, height, weight, age, and ethnicity. Previous studies demonstrated differences in some BIA variables for MCI even after adjusting for age, sex, height, and weight ( Doan et al, 2022a ). However, there is currently no standardized approach for predicting dementia or MCI using BIA variables.…”

“…demonstrated differences in some BIA variables for MCI even after adjusting for age, sex, height, and weight (Doan et al, 2022a). However, there is currently no standardized approach for predicting dementia or MCI using BIA variables.…”

Associations between objectively measured overall and intensity-specific physical activity and phase angle in older adults

“…We computed the upper- and lower-body PhAs by averaging the bioimpedance variables of the left and right arms (legs) at a frequency of 50 kHz. Whole-body PhA was determined by summing the upper and lower extremity PhAs, following a methodology outlined in a previous study 29 . The measures have been shown to be reliable and valid for assessing PhA in adults 30 .…”