Segmental dyskinesia in Wolff–Parkinson–White syndrome: A possible cause of dilatative cardiomyopathy

Fazio, Giovanni; Mongiovì, Maurizio; Sutera, Loredana; Novo, Giuseppina; Novo, Salvatore; Pipitone, Salvatore

doi:10.1016/j.ijcard.2006.11.109

Cited by 53 publications

(58 citation statements)

References 6 publications

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“…Three asymptomatic patients showed a basal septal left ventricular functional aneurysm on echocardiographic examination. We found its origin in a left ventricular dysfunction [40]. The results of these studies have been already published [40].…”

Section: Resultsmentioning

confidence: 57%

“…We found its origin in a left ventricular dysfunction [40]. The results of these studies have been already published [40]. In 76 asymptomatic patients, a treadmill test was performed; 16 children showed a complete and abrupt disappearance of the delta wave.…”

Section: Resultsmentioning

confidence: 72%

“…In our case record, three patients suffering from asymptomatic ventricular pre-excitation developed dilatative cardiomyopathy. The results of such analyses were previously published by our team [40].…”

Section: Discussionmentioning

confidence: 97%

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Asymptomatic ventricular pre-excitation in children

Fazio

Mossuto²,

Basile³

et al. 2009

Journal of Cardiovascular Medicine

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Section: Resultsmentioning

confidence: 57%

Section: Resultsmentioning

confidence: 72%

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Asymptomatic ventricular pre-excitation in children

Fazio

Mossuto²,

Basile³

et al. 2009

Journal of Cardiovascular Medicine

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“…In those reports, most patients exhibited right septal or posteroseptal accessory pathways. [7][8][9][10][11] with WPW syndrome with a right-sided free-wall accessory pathway and dilated cardiomyopathy (DCM), in which LV function improved following RF ablation. 12) In patients with decreased LV cardiac function, such as those with DCM, LV dyssynchrony can further compromise cardiac function.…”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6] Recently, an accessory pathway has been reported to contribute to LV septal dyskinesia and LV dysfunction in the absence of documented SVT. [7][8][9][10][11] Many patients exhibit right septal or posteropesptal accessory pathways. Herein, we report a case of WPW syndrome with right-sided free-wall accessory pathway and LV dysfunction.…”

Section: Introductionmentioning

confidence: 99%

An Asymptomatic Case of Wolff‐Parkinson‐White Syndrome with Right‐sided Free‐wall Accessory Pathway and Left Ventricular Dysfunction

Mine

Kodani

Hamaoka

et al. 2011

Journal of Arrhythmia

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A 16-year-old girl with a known history of asymptomatic Wolff-Parkinson-White syndrome exhibited signs of left ventricular (LV) septal akinesia and LV dysfunction during routine follow-up. A 12-lead surface ECG showed pre-excitation, a predominantly negative delta wave in V 1 and left axis deviation, which was consistent with the presence of a right free-wall accessory pathway. Radiofrequency ablation of the anterolateral right atrium around the local shortest atrium-to-ventricle interval created the accessory pathway block. An echocardiogram taken one month after the procedure revealed that LV septal wall motion had normalized and that LV ejection fraction had improved from 50% before the ablation to 64% after the ablation. Most previous reports of asymptomatic patients of WPW with LV septal dyskinesia and dysfunction have described right septal or posteroseptal accessory pathways. This patient reported here represents a rare case with right free-wall accessory pathway and LV dysfunction without tachycardia. (J Arrhythmia 2011; 27: 145-149)

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Left ventricular dyssynchrony in pre-excitation syndrome: effect of accessory pathway location and reversibility after ablation therapy

et al. 2012

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We sought to evaluate the effects and reversibility of different locations of accessory pathways (AP) on left ventricular dyssynchrony (LVdys). The acute and chronic effects of AP were evaluated in a canine model (n = 11) and in patients with pre-excitation syndrome (n = 25). Pre-excitation was simulated in the canine model by applying VDD-type epicardial ventricular pacing near the atrioventricular (AV) groove with 50-ms AV interval after median thoracotomy, at five different sites in each animal. For the simulation of pre-excitation through the septal accessory pathway, right basal septal pacing was performed using a transvenous lead. Left ventricular dyssynchrony was measured by a two-dimensional speckle-tracking technique: before and during pacing in the canine model, and before and within 24 h after the ablation in patients with Wolff-Parkinson-White (WPW) syndrome. In the canine model, the most prominent intraventricular LVdys was observed in left lateral pre-excitation (P < 0.001). In patients with pre-excitation syndrome, LVdys was greatest in patients with left free wall accessory pathways before the ablation (P = 0.013). After catheter ablation, such a difference diminished (P = 0.619). The degree of LVdys was different according to the site of AP in both the acute model and chronic patients, and the most significant LVdys associated with pre-excitation was observed in left lateral AP. Left ventricular dyssynchrony was reversible in patients with WPW syndrome. Left ventricular dyssynchrony observed in patients with pre-excitation syndrome might be a different entity from that observed in patients with heart failure.

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Segmental dyskinesia in Wolff–Parkinson–White syndrome: A possible cause of dilatative cardiomyopathy

Cited by 53 publications

References 6 publications

Asymptomatic ventricular pre-excitation in children

Asymptomatic ventricular pre-excitation in children

An Asymptomatic Case of Wolff‐Parkinson‐White Syndrome with Right‐sided Free‐wall Accessory Pathway and Left Ventricular Dysfunction

Left ventricular dyssynchrony in pre-excitation syndrome: effect of accessory pathway location and reversibility after ablation therapy

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