Segmental leukocytoclastic vasculitis in herpes zoster

Cutaneous Vasculitis and Central Nervous System Infarctions due to Varicella Zoster Virus Vasculopathy in an Immunocompromised Patient

“…Therefore, rapid diagnosis is essential. Interestingly, our patient did not present with the classic vesicular rash of VZV but rather with cutaneous vasculitis, which is often painless, thought to be a rare manifestation of VZV infection, and reported as preceding the classic vesicular rash [3][4][5]. In our patient's case, a high degree of clinical suspicion was needed to make the diagnosis.…”

Herpes zoster in pregnancy leading to keloids and post herpetic neuralgia: A double whammy?

“…[5] A host of other sequelae have been described including erythema multiformae and segmental leukocytoclastic vasculitis, the latter two by the co-author. [6–8] In our case, HZ was responsible for local trauma leading to keloids. We hypothesize that pregnancy with increased expression of keloidal activin-A/follistatin and dark skin type are cofactors for the development of post-herpetic keloids.…”

Segmental immune disorders related to herpes zoster

“…The immune destabilization restricted to the involved dermatome would facilitate the local onset of immunity‐related disorders . In this light, the case report we are commenting upon is of the utmost importance. In fact, the segmental leukocytoclastic vasculitis of the right lower leg that preceded by two days the outbreak of typical HZ lesions on the proximal segment of the same dermatome (i.e., on the right buttock and upper leg) may be seen as a herald sign of HZ eruption.…”

“…The segmental alteration of the neuroimmune control may have paved the way for the occurrence of an immunity‐related vasculitis confined to that terminal site. Therefore, it turns out that HZ‐related immune changes and immune disorders may appear “beyond zoster” as well as “before zoster.”…”