The relative value of simple bedside M-mode and two-dimensional échocardiographie
indices and their combinations for the estimation of the left ventricular
ejection fraction (LYEF) in a single, large group of patients with acute
myocardial infarction (AMI) has never been reported. Therefore, 79 patients
with AMI were studied by echocardiography and radionuclide angiography
within 12 h during the 2nd week following AMI. Parameters of left ventricular
function by traditional M-mode indices (dimensions, fractional shortening,
mitral-septal distance), by two-dimensional parameters (wall motion index,
LVEF by Baran and by a truncated cone model), by statistical integration and
by subjective evaluation were compared with radionuclide LVEF by linear
regression. There was a clear trend towards a better accuracy by subjective
evaluation of LVEF as compared with single parameter two-dimensional and
M-mode methods. However, this difference of accuracy was only statistically
significant with regard to M-mode dimensional parameters (R2 = 0.80 versus
R^2 = 0.49 to R^2 = 0.24, p < 0.05). Thus, estimates of the LVEF can be
obtained by multiple échocardiographie approaches which are all moderately
inaccurate. The combination of parameters (wall motion index and end-systolic
dimension) increased accuracy, but did not reach statistical significance.
Estimates of LVEF based on a wall motion index are obtained in virtually all
patients and have the additional advantage of providing data on the regional
function in the same échocardiographie examination, contrary to subjective
estimates of LVEF. Therefore, despite its inaccuracy, wall motion analysis
appears to be the best presently known échocardiographie method for bedside
estimation of LVEF in AML