Segmental replacement of the thoracic esophagus with woven teflon

Intrathoracic esophageal replacement in the dog with the use of an artificial esophagus composed of a collagen sponge with a double-layered silicone tube

“…However, these have consisted mainly of synthetic materials and, therefore, carry a risk of serious complications, such as leakage, [1][2][3][4][5][6][7] infection, [3][4][5] ulceration, 8,9 granulation, 1,2,[6][7][8][9][10] and migration of the prosthesis. [2][3][4][5][6][7]10 Formerly, migration of the prosthesis was considered to be the major problem to be overcome.…”

“…However, these have consisted mainly of synthetic materials and, therefore, carry a risk of serious complications, such as leakage, [1][2][3][4][5][6][7] infection, [3][4][5] ulceration, 8,9 granulation, 1,2,[6][7][8][9][10] and migration of the prosthesis. [2][3][4][5][6][7]10 Formerly, migration of the prosthesis was considered to be the major problem to be overcome. 1,10 However, when we examined these results carefully, we found that the unexpected migration of the prosthesis induced neo-epithelialization at the reconstructed site, whereas such epithelialization did not occur when the prosthesis remained at the implantation site.…”

“…1,10 However, when we examined these results carefully, we found that the unexpected migration of the prosthesis induced neo-epithelialization at the reconstructed site, whereas such epithelialization did not occur when the prosthesis remained at the implantation site. [1][2][3][4][5][6][7] We have therefore manufactured an artificial esophagus using atelocollagen sponge with a silicone tube stent. [11][12][13][14][15][16] After new host tissue has regenerated at the reconstruction site, 17,18 the inner silicone tube is designed to be dislodged to prevent any anastomotic granulation and ulceration.…”

Esophageal tissue engineering: from bench to bedside

“…Attempts to perform esophageal replacement using artificial nonabsorbable materials, such as Teflon, polyethylene terephthalate (Dacron), expanded polytetrafluoroethylene, or silicone, have failed because these materials are not biocompatible, resulting in chronic infection, anastomotic leakage, material extrusion, and strictures. Although it has been performed in the past, esophageal allotransplantation is not a realistic option because of the complexity of the esophageal vascular anatomy and the necessity for chronic immunosuppression.…”

Long Oesophageal Gaps - A New Surgical Technique

“…Fryfogle replaced segments of the thoracic oesophagus in dogs using silicon rubber prostheses of varying rigidity [15]. Morfit and Mark used teflon prostheses to replace the thoracic oesophagus [25,27]. Kamal, on the other hand, used a marlex mesh to replace Group B, incomplete gap (L4 -L9): a wedge segment of the oesophagus was excised (10 -20 mm long) after division of the oesophagus and a Silastic tube was anastomosed to the inner mucosa of both oesophageal edges 5 mm from the edge, using a prolene 7/0 suture to perform a single layer continuous anastomosis.…”