This study provides an overview of the Diabetic Retinopathy (DR) detection in human eyes utilizing various preprocessing and segmentation approaches. There are various ways for segmenting the blood veins in the retina. It is possible to determine whether or not the eyes have DR if the retinal nerve fibers have been segmented. This detection is determined by the location of the Retinal nerve fiber layer (RNFL). DR affects nerve fibers with a small total area. If the nerve fiber is large, the eyes are not damaged by DR and thus it is healthy. It is a prominent truth that diabetes has a significant impact on human health and damage every organ, including the eyes. Because the optical nerve is linked to the brain, this DR will influence vision loss in humans. Images of the retinal fundus are frequently utilized to detect and analyze diseases on infected images. Machine learning algorithms struggle to analyze raw retinal fundus images. As a result, a survey is being conducted in this area. In this way, the most current works by diverse authors from across the world are presented in this context. DR is one of the severe infections that may occur in the eyes. According to the WHO – United Nations study, this disease is the second most common among humans. As a result, eye care must be given top priority. This disease is caused by a decrease in the nerve layer of the retina. If the RNFL shrinks, the optic nerve that connects to the brain gets damaged, resulting in vision loss. This document just provides a basic overview of diabetic retinopathy.