SEIN12 Analyse de la quantite de tissu prelevee par les aiguilles de macrobiopsies mammaires

Korvin, B. De; Tas, Patrick; Mesbah, H.; Lay, Soazig Le

doi:10.1016/s0221-0363(06)87974-6

Cited by 1 publication

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“…This type of surgical upgrade has little practical relevance. Indeed, subsequent follow‐up consists of a non‐specific biennial check‐up in women aged 50–75 years in the absence of any surgical upgrade, or an annual check‐up in cases of upgrade to atypia, as atypia are a risk factor for further breast cancer . Thus, the only potential advantage of surgery is to discover atypia in order to reduce the time interval between two mammographies.…”

Section: Discussionmentioning

confidence: 99%

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Management of radial scars/complex sclerosing lesions of the breast diagnosed on vacuum‐assisted large‐core biopsy: is surgery always necessary?

et al. 2019

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Aims The diagnosis of radial scars/complex sclerosing lesions (RSs/CSLs) onpercutaneous biopsy carries a risk of histological underestimation. Consequently, surgical excision is often performed in order to exclude a possible associated malignancy. The aim of this study was to assess the rate of ‘upgrade to carcinoma’ upon subsequent surgical excision of RS/CSL cases diagnosed on vacuum‐assisted large‐core biopsy (VALCB). We also analysed the risk factors for upgrade in order to determine a subset of patients who could avoid surgery and benefit from conservative management with clinical and imaging follow‐up. Methods and results This was a retrospective observational single‐centre study on 174 consecutive RS/CSL cases diagnosed on VALCB from May 2008 to October 2015. Univariate analysis was performed to identify clinical, radiological and histological risk factors for upgrade. Surgical excision was performed following VALCB diagnosis of 88 RS/CSL cases with or without associated atypia. The overall rate of surgical upgrade to carcinoma was 9.1% (8/88). None of the benign biopsies without atypia was surgically upgraded. Additional to atypia, risk factors for upgrade were non‐incidental finding of the RS/CSL, the mammographic appearance, and the number of fragments obtained during the biopsy procedure (P < 0.05). Conclusion We demonstrate that VALCB revealing an RS/CSL is reliable for excluding malignancy when there is no associated atypia and when radiological and histological findings are concordant. In such cases, surgery can be avoided in favour of clinical and imaging follow‐up. When an RS/CSL is associated with atypia, the decision to perform surgical excision depends on other associated risk factors.

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Section: Discussionmentioning

confidence: 99%

“…Modalities of sampling were analysed, including needle size, type of imaging guidance, and number of fragments sampled. We studied a group of patients in whom six or more fragments were sampled with an 8‐gauge needle, because this allows harvesting of a greater weight of tissue than 12 fragments sampled with 10‐gauge needle …”

Section: Methodsmentioning

confidence: 99%