Oceanic transform faults (TFs) are steeply dipping fault segments of young oceanic lithosphere bounded between mid-ocean ridge spreading centers. They are thought to have a simple structure in comparison to their continental counterparts given that the composition of the ocean crust and upper mantle is relatively homogenous and generally lacks the complex lateral variability commonly evident in the continental crust (e.g., Behn et al., 2007;Wolfson-Schwehr & Boettcher, 2019). Along the axis of an oceanic TF, lithospheres of different age, and thus with different thermal and mechanical properties, interact.Ridge-transform plate boundaries may also enhance hydrothermal circulation, substantially impacting geophysical, geochemical, and biological processes (e.g., Hensen et al., 2019). Such phenomena are plausibly very typical in marine transform systems. TFs themselves may exhibit fault zone damage which can also contribute to hydrothermal circulation and alteration along the transform valley (Froment et al., 2014;Kohli et al., 2021). Exposure of altered peridotites and gabbro at detachment faults along fracture zones and core complexes (Blackman Abstract Oceanic transform faults are intriguing in that they do not produce earthquakes as large as might be expected given their dimensions. We use 1-year of local seismicity (370 events above M C = 2.3) recorded on an array of ocean bottom seismometers (OBSs) and geophysical data to study the seismotectonic properties of the Chain transform, located in the equatorial Mid-Atlantic. We extend our analysis back in time by considering stronger earthquakes (M W ≥ 5.0) from global catalogs. We divide Chain into three areas (east, central, and west) based on historical event distribution, morphology, and multidimensional OBS seismicity cluster analysis. Seismic activity recorded by the OBS is the highest at the eastern area of Chain where there is a lozenge-shaped topographic high, a negative rMBA gravity anomaly, and only a few historical M W ≥ 5.5 events. OBS seismicity rates are lower in the western and central areas. However, these areas accommodate the majority of seismic moment release, as inferred from both OBS and historical data. Higher b-values are significantly correlated with lower rMBA and with shallower bathymetry, potentially related to thickened crust. Our results suggest high lateral heterogeneity along Chain. Patches with moderate to low OBS seismicity rates that occasionally host M W ≥ 6.0 earthquakes are interrupted by segments with abundant OBS activity but few historical events with 5.5 ≤ M W < 6.0. This segmentation is possibly due to variable fluid circulation and alteration, which may also change in time.Plain Language Summary Oceanic transform faults (TFs) typically host earthquakes much smaller than expected based on their total seismogenic area. We study the seismotectonic properties of the Chain TF by combining 1-year of seismicity recorded by an ocean bottom seismometer (OBS) array with geophysical data (bathymetry, tidal height, gravity anomalies)...