This article investigated the construction conditions of the pile foundation in the Wuxing section of the “Shanghai Suzhou Huzhou” railway bridge project. To test the reliability of large diameter connectors, it has established a finite element model with ABAQUS software for numerical simulation. Based on on-site tests, the reliability of the connection between the pipe pile and the cover steel was studied. According to the simulation results, when the load is P= 900 kN, the displacements of A2 and A3 steel pipe piles are 55.8 mm and 60.1 mm, respectively. The load-displacement relationship shows a high-order curve distribution. According to the results of on-site experiments, the displacements are 77.9 mm and 60.2 mm, respectively. The load-displacement relationship is linear. The results for the simulation and on-site testing are consistent. This study provides a basis to the research on the reliability of the connection between large-diameter steel pipe piles.