ABSTRACT. During an earthquake, the nonlinearity of the bridge structure mainly occurs at the supports, bridge piers and restrainers. When entering nonlinear stage, members of the bridge structure affect the elasto-plastic seismic response of the whole structure to a certain extent; for multi-span continuous bridges, longitudinal restrainers can be installed on the movable piers to optimise the distribution of seismic force and enable the movable piers to bear a certain amount of seismic effect. In order to evaluate the effect of nonlinearity of restrainer and supports on the elasto-plastic seismic response of continuous girder bridge, analytical models of continuous girder bridge structure considering the nonlinearity of movable supports, restrainers and bridge piers were built and the nonlinear time history analysis was conducted to evaluate the effect of nonlinearity of restraining devices and supports on the elasto-plastic seismic response of continuous girder bridge. Relevant structural measures and recommendation were made to reduce the seismic response of the fixed piers of the continuous girder bridge.