The earthquake is one of the most devastating natural hazards that most of the Iranian cities. District 9 of Tehran will be vulnerable due to old residential texture, proximity to North Tehran fault and industrial land use in case of earthquake. Therefore, reducing the vulnerability to this natural disaster is one of the main goals of this study. In the present research, to evaluate vulnerability due to earthquake hazard, 10 indices are studied as effective factors in cities buildings vulnerability. These factors are selected on the basis of indices in previous studies. Indices involving materials type, type of facade building density, the age of building, the number of floors, ground area of buildings, compatibility of adjacent users, distance from the fault, geology formation and width of passageways are analyzed by using computational method of ANP scored by experts. The criteria weight is applied in effective layers in vulnerability. At last, by integrating the layers in GIS environments, general vulnerability map is extracted in the area. In order to evaluate the buildings vulnerability against earthquake, data obtained and from ANP analysis were made fuzzy. Finally, vulnerability map in district 9 of Tehran against earthquake was extracted. The research results show that if earthquake occurs, in district 9 of Tehran, 19.46% and 10.69% of buildings respectively have trivial and low vulnerability, while 50.29 percent of buildings have medium vulnerability. Also, 17.62% and 1.91% of building have high and very high vulnerability respectively, or they are completely damaged.