The western part of the Bohemian Massif (West Bohemia/Vogtland region) is characteristic in the relatively frequent recurrence of intraplate earthquake swarms and in other manifestations of past-to-recent geodynamic activity. In this study we derived 1Danisotropic qP-wave model of the upper crust in the seismogenic West Bohemia/Vogtland region by means of joint inversion of two independent data sets -travel times from controlled shots and arrival times from local earthquakes extracted from the WEBNET seismograms. We derived also simple 1-D P-wave and S-wave isotropic models. Reasons for deriving these models were: (a) only simplified crustal velocity models, homogeneous half-space or 1D isotropic layered models of this region, have been derived up to now and (b) a significant effective anisotropy of the upper crust in the region which was indicated recently by S-wave splitting. Both our anisotropic qP-wave and isotropic P-and S-wave velocity models are constrained by four layers with the constant velocity gradient. Weak anisotropy for P-waves is assumed. The isotropic model is represented by 9 parameters and the anisotropic one is represented by 24 parameters. A new robust and effective optimization algorithm -isometric algorithm -was used for the joint inversion. A two-step inversion algorithm was used. During the first step the isotropic P-and S-wave velocity model was derived. In the second step, it was used as a background model and the parameters of anisotropy were sought.Our 1D models are adequate for the upper crust in the West Bohemia/Vogtland swarm region up to a depth of 15 km. The qP-wave velocity model shows 5% anisotropy, the minimum velocity in the horizontal direction corresponds to an azimuth of 170°. The isotropic model indicates the V P /V S ratio variation with depth. The difference between the hypocentre locations based on the derived isotropic and anisotropic models was found to be several hundreds of meters. K e y w o r d s : West Bohemia/Vogtland region, earthquake swarm, anisotropy, 1D velocity model, inverse problem, earthquake location Stud. Geophys. Geod., 49 (2005), 501−524 501 © 2005 StudiaGeo s.r.o., Prague J. Málek et al.