Seizure free status as a good predictor for quality of life of temporal lobe epilepsy patients after amygdalohippocampectomy

Arifin, Muhamad Thohar; Ashari, Ashari; Brilliantika, Surya Pratama; Bunyamin, Jacob; Hardian, Hardian; Brotoarianto, Happy Kurnia; Fitrikasari, Alifiati; Muttaqin, Zainal

doi:10.15562/bmj.v9i3.2141

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some researchers claim that QoL may also be influenced by surgical treatment [ 25 , 26 ], but data on the impact of individual factors that would be responsible for the change in the well-being of patients after surgery are inconclusive due to the heterogeneity of the studied groups, the lack of repeatable measurement methods, and the heterogeneity of the studied variables. Available data suggest that the factors that may be associated with a patient’s psychological outcome after surgery include seizure-free status, time of seizure freedom, side effects of surgery, intake of epileptic drugs, side effects of those drugs, employment, and the presence of aura [ 27 , 28 ]. However, due to the inconsistency of the conclusions, further research is needed in this area.…”

Section: Introductionmentioning

confidence: 99%

Determinants of the Quality of Life in Patients with Drug-Resistant Temporal Lobe Epilepsy: A Comparison of the Results before and after Surgery

Bala,

Olejnik,

Kułak

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

Drug-resistant temporal lobe epilepsy is associated with a reduction in the quality of life of patients. The aim of this study was to compare the quality of life before and after the surgical treatment of epilepsy and to assess factors that may affect the well-being of patients after surgery. The study involved 168 patients with drug-resistant temporal lobe epilepsy. All of them were examined twice: once before and again one year after surgery. Two questionnaires were used in the study: the Quality of Life in Epilepsy Inventory-Patient-Weighted and Hospital Anxiety and Depression Scale and one that collected data on selected demographic and clinical variables. The results showed that patients scored significantly higher in quality of life and lower in depression and anxiety after surgery; however, this only applied to patients with a good outcome of treatment (Engel Class I and Class II). Patients with an unfavorable outcome of surgical treatment (Engel Class III and Class IV) achieved significantly worse results in all examined variables. Correlational analysis showed a relationship between select aspects of quality of life and the level of depression and anxiety, as well as the frequency of seizures and age at epilepsy onset. There was no significant relationship with age, sex, education, or number of prescribed antiepileptic drugs. The study confirms the significant relationship between the quality of life and the effectiveness of surgical treatment, indicating the relationship between patients’ well-being and selected clinical indicators.

show abstract