Seizure-induced reversible MRI abnormalities in status epilepticus: A systematic review

Mariajoseph, Frederick P.; Sagar, Parveen; Muthusamy, Subramanian; Amukotuwa, Shalini A.; Seneviratne, Udaya

doi:10.1016/j.seizure.2021.09.002

Cited by 27 publications

(10 citation statements)

References 31 publications

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“…These changes are variably referred to as peri-ictal MRI abnormalities (PMA), seizure-induced reversible MRI abnormalities. 1,2 While the imaging features of PMAs are well described, their evolution and clinical significance are not as well understood. The most common appearance of PMA is increased diffusion-weighted imaging (DWI) signal with decreased or normal apparent diffusion coefficient (ADC) and increased T2/fluid-attenuated recovery (FLAIR) signal.…”

Section: Commentarymentioning

confidence: 99%

Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?

Gaspard

2023

Epilepsy Curr

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Section: Commentarymentioning

confidence: 99%

Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?

Gaspard

2023

Epilepsy Curr

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“…Unlike neuroimaging changes following anoxic injury that reverse over days or weeks, 4 these DWI findings characteristically reverse over weeks to months following cessation of seizure activity 43,46 . One systematic review of 49 patients with nonconvulsive status epilepticus reported seizure‐related MRI abnormalities took a median of 3 months to resolve, ranging from hours to years on follow‐up imaging 47 …”

Section: Seizure Activitymentioning

confidence: 99%

Neuroimaging mimics of anoxic brain injury: A review

Sharma

Birnhak

Sanborn

et al. 2023

Journal of Neuroimaging

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Diffuse cortical diffusion changes on magnetic resonance imaging (MRI) are characteristically ascribed to global cerebral anoxia, typically after cardiac arrest. Far from being pathognomonic, however, this neuroimaging finding is relatively nonspecific, and can manifest in a myriad of disease states including hypoxia, metabolic derangements, infections, seizure, toxic exposures, and neuroinflammation. While these various conditions can all produce a neuroimaging pattern of widespread cortical diffusion restriction, many of these underlying causes do have subtly unique imaging features that are appreciable on MRI and can be of clinical and diagnostic utility. Specific populations of neurons are variably sensitive to certain types of injury, whether due to differences in perfusion, receptor type density, or the unique tropisms of infectious organisms. In this narrative review, we discuss a number of distinct etiologies of diffuse cortical diffusion restriction on MRI, the unique pathophysiologies responsible for tissue injury, and the resulting neuroimaging characteristics that can be of assistance in differentiating them. As widespread cortical injury from any cause often presents with altered mental status or coma, the differential diagnosis can be enhanced with rapid acquisition of MRI when clinical history or detailed physical examination is limited. In such settings, the distinct imaging features discussed in this article are of interest to both the clinician and the radiologist.

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“…CLN is a long-term sequela of SRMA, and radiological changes can sometimes persist for several years. 6,8 The characteristics and evolution of SRMA are not clearly understood, hence the difficulty in distinguishing epilepsy-associated lesions from tumours or other pathology. The history, clinical presentation and serial imaging can aid in determining the natural history and evolution of CLN in such cases.…”

Section: Cortical Laminar Necrosis Mimicking Leptomeningeal Recurrenc...mentioning

confidence: 99%

Cortical laminar necrosis mimicking leptomeningeal recurrence in a child with medulloblastoma and epilepsy

Mironova,

Benjamin,

Zacharoulis

et al. 2023

Pediatric Blood & Cancer

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Seizure-induced reversible MRI abnormalities in status epilepticus: A systematic review

Cited by 27 publications

References 31 publications

Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?

Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?

Neuroimaging mimics of anoxic brain injury: A review

Cortical laminar necrosis mimicking leptomeningeal recurrence in a child with medulloblastoma and epilepsy

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