Selected application of peptide molecules as pharmaceutical agents and in cosmeceuticals

Negahdaripour, Manica; Owji, Hajar; Eslami, Mahboobeh; Zamani, Mozhdeh; Vakili, Bahareh; Sabetian, Soudabeh; Nezafat, Navid; Ghasemi, Younes

doi:10.1080/14712598.2019.1652592

Cited by 20 publications

(12 citation statements)

References 128 publications

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“…Nutrition is a promising strategy for cellular maintenance and renewal, and for erasing the effects of skin aging, that is also healthy and safe. Peptide molecules, especially small fragments (2-20 amino acids), have been investigated as a safe, emerging therapy for the care of skin, nails, and hair [5,6]. Recently, the skin-care industry has begun to manufacture peptide-based products, including creams, lotions, and nutritional supplements [6].…”

Section: Introductionmentioning

confidence: 99%

Anti-aging skin and antioxidant assays of protein hydrolysates obtained from salted shrimp fermented with Salinivibrio cibaria BAO-01

Anh

Yang

2020

JABC

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This study focused on the preparation and characterization of anti-wrinkle peptides from the salted and fermented shrimp (Acetes japonicus) inoculated with Salinivibrio cibaria BAO-01 (SFSC). The results showed the proximate composition of SFSC to be 9.23% water, 75.32% protein, 0.23% fat, and 13.3 mg/g ash. Interestingly, the S. cibaria fermentation significantly increased the amount of methionine, leucine, and arginine. The in vitro antioxidant activity was assayed by the diphenylpicrylhydrazyl method and its IC 50 value was found to be 43.02±2.84 µg/mL. It was observed to inhibit the activity of elastase, tyrosinase, collagenase, and hyaluronidase. The IC 50 values of SFSC were 182.75±12.38 µg/mL for anti-elastase activity, 186.78±7.95 µg/mL for anti-tyrosinase activity, 444.4±34.81 µg/mL for anti-collagenase activity, and 1447.95±28.92 µg/mL for anti-hyaluronidase activity. These results suggest that salted and fermented shrimp has strong potential for the development of nutricosmetic products.

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Section: Introductionmentioning

confidence: 99%

Anti-aging skin and antioxidant assays of protein hydrolysates obtained from salted shrimp fermented with Salinivibrio cibaria BAO-01

Anh

Yang

2020

JABC

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“…Peptide-based cosmeceuticals acting against both intrinsic and extrinsic aging and improving the health and appearance of skin are becoming increasingly popular. Bioactive peptides have either pharmaceutical or cosmetic value and open a new avenue in the field of gerocosmetology [380,381]. They are used for collagen stimulation, wound healing, "botox-like" wrinkle smoothing, as well as antioxidative, antimicrobial, and whitening effects [378].…”

Section: Peptide-based Cosmeceuticalsmentioning

confidence: 99%

A Global Review on Short Peptides: Frontiers and Perspectives

et al. 2021

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Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with protein-protein interactions, which are indispensable in bio-processes. Short peptides include fundamental molecular information for a prelude to the symphony of life. They have aroused considerable interest due to their unique features and great promise in innovative bio-therapies. This work focusing on the current state-of-the-art short peptide-based therapeutical developments is the first global review written by researchers from all continents, as a celebration of 100 years of peptide therapeutics since the commencement of insulin therapy in the 1920s. Peptide “drugs” initially played only the role of hormone analogs to balance disorders. Nowadays, they achieve numerous biomedical tasks, can cross membranes, or reach intracellular targets. The role of peptides in bio-processes can hardly be mimicked by other chemical substances. The article is divided into independent sections, which are related to either the progress in short peptide-based theranostics or the problems posing challenge to bio-medicine. In particular, the SWOT analysis of short peptides, their relevance in therapies of diverse diseases, improvements in (bio)synthesis platforms, advanced nano-supramolecular technologies, aptamers, altered peptide ligands and in silico methodologies to overcome peptide limitations, modern smart bio-functional materials, vaccines, and drug/gene-targeted delivery systems are discussed.

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“…As was mentioned above, peptide synthesis continues to be one of the areas of greatest interest in organic chemistry. This is due to the fact that peptides have many diverse applications, not only in the synthesis of organic compounds, but most importantly in the food and pharmaceutical industry [ 110 , 111 , 112 ]. In this regard, in recent years mechanochemistry has played an important role in the green synthesis of these compounds [ 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 ].…”

Section: Mechanochemistrymentioning

confidence: 99%

Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions

Avila‐Ortiz

Juaristi

2020

Molecules

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One central challenge for XXI century chemists is the development of sustainable processes that do not represent a risk either to humanity or to the environment. In this regard, the search for more efficient and clean alternatives to achieve the chemical activation of molecules involved in chemical transformations has played a prominent role in recent years. The use of microwave or UV-Vis light irradiation, and mechanochemical activation is already widespread in many laboratories. Nevertheless, an additional condition to achieve “green” processes comes from the point of view of so-called atom economy. The removal of solvents from chemical reactions generally leads to cleaner, more efficient and more economical processes. This review presents several illustrative applications of the use of sustainable protocols in the synthesis of organic compounds under solvent-free reaction conditions.

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Selected application of peptide molecules as pharmaceutical agents and in cosmeceuticals

Cited by 20 publications

References 128 publications

Anti-aging skin and antioxidant assays of protein hydrolysates obtained from salted shrimp fermented with Salinivibrio cibaria BAO-01

Anti-aging skin and antioxidant assays of protein hydrolysates obtained from salted shrimp fermented with Salinivibrio cibaria BAO-01

A Global Review on Short Peptides: Frontiers and Perspectives

Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions

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