“…The short-term symptoms and the long-term metabolic sequelae ol the surgical mcnopause (Chakravarti ef d. 1077). such as osteoporosis and an increased occurrence of heart attacks, are not disputed but it is arguable that replacement o f oestrogens will overcome all of the problems of this iatrogenic endocrinopathy (Studd et al 1986) and that thc advantages oC prophylactic oophorectomy in conjunction with modern hormone replacement therapy are considerable.…”
“…The short-term symptoms and the long-term metabolic sequelae ol the surgical mcnopause (Chakravarti ef d. 1077). such as osteoporosis and an increased occurrence of heart attacks, are not disputed but it is arguable that replacement o f oestrogens will overcome all of the problems of this iatrogenic endocrinopathy (Studd et al 1986) and that thc advantages oC prophylactic oophorectomy in conjunction with modern hormone replacement therapy are considerable.…”
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