Selection of Prosthetic Materials in the Repair of Complex Abdominal Wall Defects

Reis, Marcos Campos Wanderley; Pereira, Bruno M.; Nascimento, Bartolomeu; Fraga, Gustavo Pereira

doi:10.1007/978-1-4614-6354-2_12

Cited by 1 publication

(2 citation statements)

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“…13 Meshes for clinical hernioplasty can be categorized as nonabsorbable prostheses, partially absorbable prostheses, and absorbable prostheses. 14 Among them, the common nonabsorbable materials are polypropylene (PP), polyester (PET), expanded polytetrafluoroethylene (ePTFE). 15 Absorbable mesh materials include poly(4-hydroxybutyrate), poly(glycolic acid), and carboxy cellulose (poly(glycolic acid), poly(lactic acid−glycolic acid)).…”

Section: Developments In Hernia Meshesmentioning

confidence: 99%

“…At present, there are more than 200 kinds of synthetic meshes and biologic meshes . Meshes for clinical hernioplasty can be categorized as nonabsorbable prostheses, partially absorbable prostheses, and absorbable prostheses . Among them, the common nonabsorbable materials are polypropylene (PP), polyester (PET), expanded polytetrafluoroethylene (ePTFE) .…”

Section: Developments In Hernia Meshesmentioning

confidence: 99%

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Latest Trends on the Attenuation of Systemic Foreign Body Response and Infectious Complications of Synthetic Hernia Meshes

Fang

Wang

et al. 2021

ACS Appl. Bio Mater.

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Throughout the past few years, hernia incidence has remained at a high level worldwide, with more than 20 million people requiring hernia surgery each year. Synthetic hernia meshes play an important role, providing a microenvironment that attracts and harbors host cells and acting as a permanent roadmap for intact abdominal wall reconstruction. Nevertheless, it is still inevitable to cause not-so-trivial complications, especially chronic pain and adhesion. In long-term studies, it was found that the complications are mainly caused by excessive fibrosis from the foreign body reaction (FBR) and infection resulting from bacterial colonization. For a thorough understanding of their complex mechanism and providing a richer background for mesh development, herein, we discuss different clinical mesh products and explore the interactions between their structure and complications. We further explored progress in reducing mesh complications to provide varied strategies that are informative and instructive for mesh modification in different research directions. We hope that this work will spur hernia mesh designers to step up their efforts to develop more practical and accessible meshes by improving the physical structure and chemical properties of meshes to combat the increasing risk of adhesions, infections, and inflammatory reactions. We conclude that further work is needed to solve this pressing problem, especially in the analysis and functionalization of mesh materials, provided of course that the initial performance of the mesh is guaranteed.

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Section: Developments In Hernia Meshesmentioning

confidence: 99%

Section: Developments In Hernia Meshesmentioning

confidence: 99%