1998
DOI: 10.1111/j.1528-1157.1998.tb01391.x
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Selective Amobarbital Test for the Determination of Language Function in Patients with Epilepsy with Frontal and Posterior Temporal Brain Lesions

Abstract: Summary:Purpose: Selective amobarbital tests with selective temporary inactivation of the left frontal operculum and/or the left parietotemporal cortex were performed in 5 patients with left-hemispheric epileptogenic lesions in or adjacent to classical Broca's and/or Wemicke's area. The aim was to assess language functions in these brain regions before surgery, to tailor the surgery according to the individual functional importance of these brain regions, and to predict postoperative outcome.Methods: Amobarbit… Show more

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Cited by 24 publications
(18 citation statements)
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“…The LH region generally responsible for phonological output is the left frontal operculum (Alexander, Naeser, & Palumbo, 1990;Hajek, Valavanis, Yonekawa, Schiess, Buck, & Wieser, 1998;Rosen, Fiez, Hanlon, Dromerick, Linenweber, Petersen, Raichle, & Corbetta, 1998). As discussed above, the RH hypothesis leaves open the question of the laterality of phonological output mechanisms for reading aloud in deep dyslexia.…”
Section: Phonological Output Processingmentioning
confidence: 98%
“…The LH region generally responsible for phonological output is the left frontal operculum (Alexander, Naeser, & Palumbo, 1990;Hajek, Valavanis, Yonekawa, Schiess, Buck, & Wieser, 1998;Rosen, Fiez, Hanlon, Dromerick, Linenweber, Petersen, Raichle, & Corbetta, 1998). As discussed above, the RH hypothesis leaves open the question of the laterality of phonological output mechanisms for reading aloud in deep dyslexia.…”
Section: Phonological Output Processingmentioning
confidence: 98%
“…The determination of language dominance has become an important issue in the presurgical benefit-risk evaluation of patients with brain tumors in eloquent areas and/ or intractable epilepsy (Loring et al 1990;Gerschlager et al 1998;Hajek et al 1998). An adequate evaluation demands techniques that are reliable, reproducible, repeatable, and risk-free in nature, i.e., in the best case non-invasive.…”
Section: Introductionmentioning
confidence: 99%
“…Its diagnostic yield and safety for children and adults has been proved for almost every aspect of cerebrovascular pathology [22][23][24][25][26][27][28][29] . The role of superselective angiography for the evaluation of newly formed collaterals after revascularization procedures in children with moyamoya, as well as its safety despite catheterization of the vasospasm-prone middle meningeal and temporal arteries or of the small-calibre anterior choroidal artery for an endovascular approach to distal aneurysms, was also reported by other groups [30][31][32][33][34] .…”
Section: Discussionmentioning
confidence: 99%