Selective and sensitive voltammetric determination of folic acid using graphite/restricted access molecularly imprinted poly(methacrylic acid)/SiO2 composite

Kuceki, Michele; Oliveira, Fernanda Midori de; Segatelli, Mariana Gava; Coelho, Malena Karla Lombello; Pereira, Arnaldo César; Rocha, Luana Rianne da; Mendonça, Jhessica de Cássia; Tarley, César Ricardo Teixeira

doi:10.1016/j.jelechem.2018.04.043

Cited by 24 publications

(11 citation statements)

References 31 publications

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“…As shown in Figure 6B, the plots peak currents versus scan rate for the oxidation of GA and FA show linear relationship with regression equations: I pa (μA) = 37.98 υ (V s À 1 ) + 0.696 (R 2 = 0.993) for GA and I pa (μA) = 32.19 υ (V s À 1 )À 0.072 (R 2 = 0.995) for FA. This result indicates the electrochemical reactions of GA and FA at the pretreated electrode are adsorption -controlled processes [4,26,41]. In addition, the linear relationship between the logarithm of peak current (log I) and the logarithm of scan rate (log υ) (Figure 6C) is expressed as: log I pa (μA) = 0.802 log υ (V s À 1 ) + 1.48 (R 2 = 0.990) for GA and log I pa (μA) = 0.947 log υ (V s À 1 ) + 1.46 (R 2 = 0.995) for FA.…”

Section: Effect Of Scan Ratementioning

confidence: 99%

“…Electrochemical methods have been widely applied for the determination of target analytes because they are rapid, sensitive, simple and provide information about the reaction mechanisms [27]. So far, different chemically modified electrodes have been reported for the individual electrochemical determination of GA [1,3,4,27] and FA [17,19,20,26] with high sensitivity and selectivity. However, most of these methods have some drawbacks such as, sophisticated electrode modification procedures and high cost modifiers.…”

Section: Introductionmentioning

confidence: 99%

“…Carbon paste electrode has been widely used as a working electrode for the determination of biologically active molecules due to easy modification, renewable surface, low background current, wide potential window, low ohmic resistance and low cost [15,20,26,[28][29][30]. However, the electrochemical determination of target analyte at bare carbon paste electrode sometimes leads to a decrease in electron transfer kinetics due to passivation of the surface of the electrode by adsorption of reaction products [31,32].…”

Section: Introductionmentioning

confidence: 99%

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Simultaneous Determination of Gallic Acid and Folic Acid in Fruit Juice Samples Using Square Wave Voltammetry at Electrochemically Pretreated Carbon Paste Electrode

et al. 2022

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An efficient sensor was developed for the simultaneous determination of gallic and folic acid in juice samples using an electrochemically pretreated carbon paste electrode. The electrode was characterized by CV and EIS. The electrochemical behavior of GA and FA was evaluated by CV and SWV. The electrode exhibited high electrocatalytic activity towards GA and FA due to high surface area. Under the optimized condition, linear plots in the ranges of 0.08–13 μM and 0.1 to 15 μM were obtained for GA and FA, respectively. The proposed method was successful for the simultaneous determination of GA and FA in juice samples with satisfactory recovery.

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Section: Effect Of Scan Ratementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Simultaneous Determination of Gallic Acid and Folic Acid in Fruit Juice Samples Using Square Wave Voltammetry at Electrochemically Pretreated Carbon Paste Electrode

et al. 2022

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“…No anodic oxidation of the molecule was reported either on the second oxidation step of the CV due to the polymer that is prone to overoxidize at 0.7-0.8 V/Ag and hinders the electrochemical signal of the analyte [25,26,29,30]. The polymeric structures undergo an overoxidation process at 0.8 V/Ag and the capacitive current blocks the potential anodic peak of the analyte and no signal was detected.…”

Section: The Electrochemical Oxidation Of Famentioning

confidence: 99%

Selective Detection of Folic Acid Using 3D Polymeric Structures of 3-Carboxylic Polypyrrole

Melinte

Cernat

Irimes

et al. 2020

Sensors

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The detection of folic acid in biological samples or pharmaceutical products is of great importance due to its implications in the biological functions of the human body, along with the development and growth of the fetus. The deficiency of folic acid can be reversed by the intake of different pharmaceutical formulations or alimentary products fortified with this molecule. The elaboration of sensing platforms represents a continuous work in progress, a task in which the use of conductive polymers modified with different functionalities represents one of the outcoming strategies. The possibility of manipulating their morphology with the use of templates or surfactants represents another advantage. A sensing platform based on carboxylic functionalized polypyrrole was synthesized via the electrochemical approach in the presence of a polymeric surfactant on a graphite-based surface. The sensor was able to detect the folic acid from 2.5 μM to 200 μM with a calculated limited of detection of 0.8 μM. It was employed for the detection of the analyte from commercial human serum and pharmaceutical products with excellent recovery rates. The results were double checked using an optimized spectrophotometric procedure that confirmed furthermore the performances of the sensor related to real samples assessment.

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“…The active form of FA is folate, which exists in food so that human body needs it for its function. FA does not become biologically activated unless it is transformed into an active form of folate [1]. If folic acid introduces into body through certain diets, it generally should be converted to the folate form for effective application.…”

Section: Introductionmentioning

confidence: 99%

A nano-sensor based on screen printed electrode (SPE) for electro-chemical detection of vitamin B9

Aflatoonian

Tajik

Ekrami‐Kakhki

et al. 2020

Eurasian Chem. Commun.

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The present study designed an electro-chemical instrument with high sensitivity and selectivity on the basis of a SPE modified with La +3 /Co3O4 nano-cubes in order to analyze vitamin B9. It was confirmed that this sensor possesses very good electronmoderating behaviors to oxidize vitamin B9 in a 0.1 M phosphate buffer solution (PBS) (pH=7.0). In addition, according to optimal conditions (pH=7.0), a potential around 110 mV less positive than the one in the un-modified electrodes is required for vitamin B9 oxidation at this electrode surface. This technique limit of determination for vitamin B9 has been estimated to be 0.3 μM (S/N = 3). Responses have been linear in concentrations range between 1.0 and 600.0 μM. The modified electrode has been applied to detect vitamin B9 in real specimens, which was accompanied by acceptable outputs. Experiments showed that La +3 /Co3O4 nano-cubes will be valuable electrode materials providing a high ratio of surface to volume that enhances sensitivity. The study introduces a novel sensor with simpleness, quickness, sensitivity, and affordability features to quantify vitamin B9. A nano-sensor based on screen printed electrode (SPE) for electro-chemical detection of vitamin B 9 .

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Selective and sensitive voltammetric determination of folic acid using graphite/restricted access molecularly imprinted poly(methacrylic acid)/SiO2 composite

Cited by 24 publications

References 31 publications

Simultaneous Determination of Gallic Acid and Folic Acid in Fruit Juice Samples Using Square Wave Voltammetry at Electrochemically Pretreated Carbon Paste Electrode

Simultaneous Determination of Gallic Acid and Folic Acid in Fruit Juice Samples Using Square Wave Voltammetry at Electrochemically Pretreated Carbon Paste Electrode

Selective Detection of Folic Acid Using 3D Polymeric Structures of 3-Carboxylic Polypyrrole

A nano-sensor based on screen printed electrode (SPE) for electro-chemical detection of vitamin B9

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