Selective antimicrobial and antibiofilm activity of metal–organic framework NH2-MIL-125 against Staphylococcus aureus

Khan, Zeeshan Ahmad; Goda, Emad S.; Rehman, Aafaq ur; Sohail, Muhammad

doi:10.1016/j.mseb.2021.115146

Cited by 34 publications

(16 citation statements)

References 33 publications

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“…Metal ions as a type of common antibacterial agents, are not only effective in bacteria killing, where in the case of biofilms, they also show scavenging ability, such as the Co 2+ , Mg 2+ , and Ti 4+ from Co-based MOFs, 220 Mg-based MOFs, 221 and Ti-based MOFs. 222 By releasing metal ions, these MOFs can kill the bacteria, and thus prevent the formation of a biofilm. When metal ions are combined with antibiotics, their activity against biofilms is further enhanced, such as ZIF-8 combined with vancomycin 219 and MIL-88B(Fe) combined with 5-(4-chlorophenyl)- N -(2-isobutyl)-2-aminoimidazole (antibiofilm compound).…”

Section: Mof-based Materials Against Bacterial Biofilmsmentioning

confidence: 99%

Metal organic framework-based antibacterial agents and their underlying mechanisms

2022

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Section: Mof-based Materials Against Bacterial Biofilmsmentioning

confidence: 99%

Metal organic framework-based antibacterial agents and their underlying mechanisms

2022

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“…After assessment of the antibacterial activity, the antibiofilm activity of the fabricated films was evaluated by crystal violet staining [ 13 , 44 ]. Here, PCL film was used as a control.…”

Section: Resultsmentioning

confidence: 99%

“…The antibacterial property of the fabricated films was investigated by the disk diffusion and broth dilution methods. [ 42 , 43 ] The antibiofilm activity of the films was investigated by the crystal violet assay [ 13 , 44 ].…”

Section: Methodsmentioning

confidence: 99%

“…To investigate the antibiofilm activities of the fabricated films against E. coli and S. aureus, the static biofilm formation was assayed in 24-well polystyrene plates [ 13 , 44 ]. In brief, cells in LB at initial turbidity of 0.05 at 600 nm (OD 600 ) were cultured with all of the fabricated films (PCL, f-PANI, HCP-PANI, and HCP-SPANI) for 24 h without shaking at 37 °C.…”

Section: Methodsmentioning

confidence: 99%

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Antibacterial Activity of Polyaniline Coated in the Patterned Film Depending on the Surface Morphology and Acidic Dopant

2022

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We have fabricated poly(ε-caprolactone) (PCL) films with flat and honeycomb-patterned (HCP) structures to coat polyaniline (PANI) on the film surface. In addition, the effect of chemical modification of PANI by sulfuric acid (H2SO4) was also studied for antibacterial activity. The flat and HCP PCL films were obtained by simple evaporation of the solvent and via the breath figure (BF) method, respectively. The morphology and chemical composition of PANI coated on the film surface were evaluated by scanning electron microscopy (SEM) and X-ray spectroscopy (EDX). Fourier transform infrared spectroscopy (FT-IR) and thermogravimetric analyses (TGA) were obtained to identify the PANI coating. The wettability and conductivity of the films were also measured. Applicational aspects were evaluated by assessing antibacterial and antibiofilm activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The EDX, TGA, and FT-IR findings indicated chemical modification of PCL film by PANI and H2SO4. The conductivity of the films was increased by the coating of PANI to the patterned surface and additionally increased by the chemically modified PANI. The antibacterial activity was 69.79%, 78.27%, and 88% against E. coli, and 32.73%, 62.65%, and 87.97% against S. aureus, for flat PANI, HCP PANI, and H2SO4-treated HCP films, respectively. Likewise, the PANI coated flat, HCP, and H2SO4-treated HCP films inhibited E. coli biofilm formation by around 41.62%, 63%, and 83.88% and S. aureus biofilm formation by 17.81%, 69.83%, and 96.57%, respectively. The antibacterial activity of the HCP film was higher than that of flat PANI films, probably due to the higher coating of PANI on the HCP surface. Moreover, sulfonation of the HCP film with H2SO4 might have improved the wettability, thereby enhancing the antibacterial and antibiofilm properties. Our results showed that topographical changes, as well as doping, offer simple and cost-effective ways to modify the structural and functional properties of films.

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“…Therefore, developing safe and effective bacteriostatic technologies is an important research issue in the food industry. Recently, the antimicrobial nanomaterials technologies based on metal and metal oxides (silver, copper, gold, zinc, etc) have attracted much attention ( Abu Elella et al, 2021 , Khan et al, 2021 ). However, considering the use of metal nanoparticles may cause environmental hazards, the concept of “without chemically synthesized preservatives added” has attracted much attention from consumers ( Raybaudi-Massilia, Mosqueda-Melgar, Soliva-Fortuny, & Martin-Belloso, 2009 ).…”

Section: Introductionmentioning

confidence: 99%

Simultaneously enhanced stability and biological activities of chlorogenic acid by covalent grafting with soluble oat β-glucan

Luo

Meng

et al. 2023

Food Chemistry: X

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Selective antimicrobial and antibiofilm activity of metal–organic framework NH2-MIL-125 against Staphylococcus aureus

Cited by 34 publications

References 33 publications

Metal organic framework-based antibacterial agents and their underlying mechanisms

Metal organic framework-based antibacterial agents and their underlying mechanisms

Antibacterial Activity of Polyaniline Coated in the Patterned Film Depending on the Surface Morphology and Acidic Dopant

Simultaneously enhanced stability and biological activities of chlorogenic acid by covalent grafting with soluble oat β-glucan

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