Selective bone cell adhesion on formulations containing carbon nanofibers

Price, Rachel L.; Waid, Michael C.; Haberstroh, Karen M.; Webster, Thomas J.

doi:10.1016/s0142-9612(02)00609-9

Cited by 379 publications

(234 citation statements)

References 11 publications

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“…In the currently used implants observed problem is the lack of precise adherence to tissue surfaces, which could be solved by introducing free zones eg. carbon nanofibers or nanotubes [3]. These are particularly preferred material because of their lack of interaction with human tissue.…”

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confidence: 99%

Bacterial Nanocellulose as a Microbiological Derived Nanomaterial

Stanisławska

2016

Advances in Materials Science

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Bacterial nanocellulose (BNC) is a nanofibrilar polymer produced by strains such as Gluconacetobacter xylinus, one of the best bacterial species which given the highest efficiency in cellulose production. Bacterial cellulose is a biomaterial having unique properties such as: chemical purity, good mechanical strength, high flexibility, high absorbency, possibility of forming any shape and size and many others. Such a large number of advantages contributes to the widespread use of the BNC in food technology, paper, electronic industry, but also the architecture in use. However, the greatest hopes are using the BNC in medicine. This text contains information about bacterial nanocellulose, its specific mechanical and biological properties and current applications. Keywords: nanomaterials, bacterial nanocelullose, mechanical properties, application in medicine NanomaterialsNanomaterials its specific properties owes its size. The most striking feature of nanomaterials is a large area boundaries chapter. Depending on the kind of material are the outer surfaces, as in the case of nanoparticles, nanotubes or nanofibers, in nanocrystalline materials are the internal surfaces of the section: the grain boundaries or interphase boundaries. This causes their strong chemical reactivity and a tendency to agglomerate, while diffusion occurs much faster than in the microcrystalline materials. This results include low thermal stability of these materials, much faster overlap of various kinds of phase transformation or facilitated movement of the grains with respect to each other at elevated temperature. At the same time reducing the grain size, according to the Hall-Petch relationship, it causes an increase of yield stress as well as tensile strength or hardness [1,2]. Nanomaterials can be divided by origin into 3 groups: -natural -anthropogenic (a side effect of human activity), -designed. Natural nanoparticles come mostly from thermal processes, eg. Forest fires, volcanic eruptions (eg. volcanic dust) or from the oxidation of minerals, erosion of rocks or evaporation (eg. sea salt formed during the evaporation of a drop of sea water). Anthropogenic nanomaterials are a side effect of human activity. Formed, for example. During the combustion of coal (carbon black) or during welding, or vulcanization of rubber. Nanoparticles may also arise during the mechanical working of materials by cutting, SCIENCE, Vol. 16, No. 4 (50), December 2016 sawing and grinding. Nanomaterials designed and produced in a targeted manner by man include fullerenes, nanotubes, liposomes, dendrimers or nanofibers.The range of applications of nanomaterials is still expanding. Particularly high hopes associated with their use in medicine, especially in transplantation. In the currently used implants observed problem is the lack of precise adherence to tissue surfaces, which could be solved by introducing free zones eg. carbon nanofibers or nanotubes [3]. These are particularly preferred material because of their lack of interaction with human tissu...

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confidence: 99%

Bacterial Nanocellulose as a Microbiological Derived Nanomaterial

Stanisławska

2016

Advances in Materials Science

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“…No other material can compete with their outstanding combination of mechanical, thermal and electronic properties, which makes them an outstanding reinforcement material for composites (Goller et al, 2003;Cholpek et al, 2006;Price et al, 2003;Peigney, 2003). The ideal reinforcement material would impart mechanical integrity to the composite at high loadings, without diminishing its bioactivity.…”

Section: Carbon Nanotube-reinforced Poly (Methyl Methacrylate) Nanocomentioning

confidence: 99%

Integrated Biomimemic Carbon Nanotube Composites for Biomedical Applications

Sundar¹,

Hawaldar²,

Titus³

et al. 2012

Biomedical Engineering - Technical Applications in Medicine

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“…Other work has also shown increased osteoblast alkaline phosphatase activity and calcium deposition when carbon fi bers and nanotubes were used as substrates for cell growth and increased osteoblast adhesion when a polyurethane/CNT composite was used as a substrate [20,22].…”

Section: Introductionmentioning

confidence: 96%

Nanostructured 3-D collagen/nanotube biocomposites for future bone regeneration scaffolds

et al. 2009

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The fi eld of bionanotechnology has been rapidly growing during the last few years and we can now envision a controllable integration between biological and artificial matter, where new biomimetic structures with a wide range of chemical and physical properties will promote the development of a novel generation of medical devices. In this work we describe a collagen/carbon nanotube composite which has the potential to be used as a scaffold for tissue regeneration. Because this biocomposite incorporates the advantageous properties of both collagen and carbon nanotubes, it has most of the characteristics that an ideal biomaterial requires in order to be used as an osteoinductive agent. This biocomposite is bioresorbable and biodegradable and has the desired mechanical rigidity while maintaining a three-dimensional(3-D) nanostructured surface. Tuned stability and swelling were achieved under fluid environments by varying the amount of carbon nanotubes (CNTs) incorporated into the composite. These variations can dictate the degree of interaction between fibroblastic cells and the biomaterials. Proof-of-concept was shown by performing an in vitro induced mineralization of hydroxylapatite crystals under physiological conditions. Furthermore, the ability to attach biofunctional groups to the CNT walls can open a new road for tissue regeneration since the combination of CNTs with specific growth factors or cellular ligands can create an environment capable of signaling and infl uencing specifi c cell functions. Our observations suggest that collagen/carbon nanotube biocomposites will have important uses in a wide range of biotechnological areas.

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Selective bone cell adhesion on formulations containing carbon nanofibers

Cited by 379 publications

References 11 publications

Bacterial Nanocellulose as a Microbiological Derived Nanomaterial

Bacterial Nanocellulose as a Microbiological Derived Nanomaterial

Integrated Biomimemic Carbon Nanotube Composites for Biomedical Applications

Nanostructured 3-D collagen/nanotube biocomposites for future bone regeneration scaffolds

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