Selective decrease of small sensory neurons in lumbar dorsal root ganglia labeled with horseradish peroxidase after Nd:YAG laser irradiation of the tibial nerve in the rat

Effects of 904-nm Low-Level Laser Therapy in the Management of Lateral Epicondylitis: A Randomized Controlled Trial

“…[32][33][34] It has also been demonstrated in animal studies that laser therapy results in a selective reduction of A␦-and C-fiber activity. 35 In addition, LLLT significantly increased the latency of the superficial radial nerve with a corresponding decrease in sensory nerve conduction. 36 Although our findings are promising, divergent results have been reported in other clinical trials on LLLT.…”

Effect of pulsed Nd:YAG laser radiation on action potential conduction in isolated mammalian spinal nerves

“…Some differences were evident between preparations at certain dose levels, but in general there was no consistent evidence to suggest that slowly conducting C-fibers were more or less susceptible than A␤-fibers to lasing with the pulsed Nd:YAG laser. Wesselmann et al [10,13] reported that lasing with a Q-switched Nd:YAG laser had a preferential effect on the slowly conducting and smaller diameter myelinated afferent axons in rat peripheral nerves. The CAP changes observed in the A␤-fiber CAP (Fig.…”

Efficacy of 904 nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: A double‐blind and randomize‐controlled trial

“…While the underlying mechanism is unknown, it has been demonstrated in animal studies that pulsed Nd-Yag laser therapy results in a selective reduction of A d and C fiber activity [32]. Anti-inflammatory effects have been demonstrated both in-vitro (820 nm Ga-Al-As) [33] and in-vivo (632.8 nm HeNe) [34] and a direct effect on motoricity of lymph vessels (630 nm He-Ne) [35], reducing interstitial fluid at the site of inflammation, has been described.…”