Selective feticide in late trimester: Misinterpretation

Yeh, Chang-Ching; Horng, Huann-Cheng; Wang, Peng-Hui

doi:10.1097/jcma.0000000000000664

Cited by 9 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although we are concerned with Dr. Shyr’s recommendation about the use of PHSS in the management of SPT patients with ADP, there is no doubt that the excellent therapeutic outcomes of the SPT patients with/without ADP after PHSS were indeed worthy of applause. Similar to all rare diseases or rare clinical situations, 18 it is hard to get a consensus on how manage this rare disease, due to the impossibility to obtain the data from a large sample size. However, we still emphasize the careful interpretation of data to minimize the risk of misjudgment.…”

mentioning

confidence: 99%

Organ- or function-preservation surgery is recommended, but who is a candidate?

Liu

Yang

Wang

2022

Journal of the Chinese Medical Association

Self Cite

View full text Add to dashboard Cite

mentioning

confidence: 99%

Organ- or function-preservation surgery is recommended, but who is a candidate?

Liu

Yang

Wang

2022

Journal of the Chinese Medical Association

Self Cite

View full text Add to dashboard Cite

“…Oxytocin is a potent uterotonic agent that enhances the uterine tone and contractility and is commonly used for labor induction and postpartum hemorrhage management. [1][2][3][4][5][6][7][8][9] The response of a target tissue relies on the concentration of the circulating hormone and affinity and concentration of tissue receptors. 10 Notwithstanding, considering that oxytocin contracts the uterine smooth muscle and increases the uterine tone, many clinicians favor its use during surgical evacuation for missed abortion to attempt to minimize blood loss and reduce the risk for uterine perforation.…”

Section: Introductionmentioning

confidence: 99%

The timing of intravenous oxytocin administration is crucial to minimize perioperative blood loss during first-trimester suction curettage for missed abortion

Yang

Chang

Chao

et al. 2022

Journal of the Chinese Medical Association

Self Cite

View full text Add to dashboard Cite

Background: Oxytocin is commonly used to reduce blood loss during suction curettage for missed abortion. However, the potential of oxytocin to mitigate blood loss in early pregnancy remains controversial. Based on the hypothesis that the “timing” of oxytocin administration may be a critical factor, we investigated whether the timing of intravenous (IV) administration is associated with reduced perioperative blood loss during first-trimester suction curettage for missed abortion. Methods: The medical charts of 146 patients with ultrasound-confirmed first-trimester missed abortion who underwent suction curettage with IV oxytocin administration were retrospectively reviewed. Results: Among the patients, 67 received 10 IU of IV oxytocin before suction curettage (early-oxytocin administration group), while 79 patients received 10 IU of IV oxytocin after suction curettage (late-oxytocin administration group). The demographic features between the two groups did not significantly differ. However, there was a lower proportion of nulliparous patients in the early-oxytocin administration group than in the late-oxytocin administration group (38.8% vs 60.8%, p = 0.006). The perioperative blood loss amount was significantly lower in the early-oxytocin administration group than in the late-oxytocin administration group (60 [range: 50–100] vs 100 [range: 30–250] mL, p = 0.001). Moreover, the multivariate logistic regression analysis showed that the early-oxytocin administration group had a lower risk for a perioperative blood loss amount of ≥100 mL than the late-oxytocin administration group (0.23 [range: 0.10–0.55], p = 0.001); a gestational age of 9–12 weeks (p = 0.009) was found to be associated with an increased risk for a perioperative blood loss amount of ≥100 mL. Conclusion: Compared with late-oxytocin administration, early-oxytocin administration could reduce perioperative blood loss during first-trimester suction curettage for missed abortion. However, the results require further investigation.

show abstract

“…12,13 The basic concept should be well informed that the theoretical background of combination of CT and RT is significantly different from CCRT, and the former is given for both systemic and localized therapy, but the latter is limited to localized disease (any CT given to patients based on enhanced therapeutic effect of RT). 12,13 Similar to the principle of statistics applied to the clinical data presentation, 14,15 the theoretical principle is often miss-used in the routine clinical practice. For clinical practice, combination of CT and RT is often associated with more therapy-related AEs, even though both combinations of CT and RT and CCRT will additionally augment the therapy-related toxicity, compared to RT alone.…”

mentioning

confidence: 99%