Abstract:Introduction: Selective immunoglobulin A deficiency (SIgAD) is the most common primary immunodeficiency in the Caucasian population. The current definition describes SIgAD as serum IgA level below 0.07 g/l in individuals of four years of age or older with normal immunoglobulin G and M levels, in whom other causes of hypogammaglobulinaemia have been excluded. Most patients with SIgAD are asymptomatic, but some of them suffer from recurrent infections, primarily involving the respiratory system, allergies, autoi… Show more
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