Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy

Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences

“…Similarly, our finding that processing of action-related information in PD is impaired even at a strictly semantic level replicates previous results by Ibáñez et al (2013). The crucial implication of the BG in these domains is further highlighted by reports of similar impairments in other neurodegenerative motor disorders (Bak et al, 2006;Cotelli et al, 2006;Daniele et al, 2013;Kargieman et al, 2014;Silveri & Ciccarelli, 2007).…”

“…As García and Ibáñez (2014) argue, effective diagnosis might be achieved through early detection of linguistic alterations even before other domains are affected, paving the way for timely application of cognitive stimulation programs. Also, in light of convergent results from other clinical populations (Bak et al, 2006;Cotelli et al, 2006;Daniele et al, 2013;Kargieman et al, 2014;Silveri & Ciccarelli, 2007), this prospective assessment model could be extended to other neurodegenerative diseases involving comparable language affectation (especially in the domain of action verbs) following BG damage (e.g., progressive supranuclear palsy, Huntington's disease, cortico-basal degeneration).…”

Radiological biomarkers for diagnosis in PSP: Where are we and where do we need to be?

“…However, cortical and whole‐brain rates of atrophy are greater in CBS than in PSP‐RS . Cerebral blood flow single‐photon emission computed tomography studies have demonstrated frontal and, less commonly, thalamic and striatal hypoperfusion in PSP‐RS . Findings concerning differentiating PSP‐RS from other parkinsonian disorders are lacking here, although PSP‐RS may show greater frontal hypoperfusion than PD .…”

“…208 Longitudinal MR studies have shown increased rates of whole-brain, cortical, and midbrain atrophy and SCP diffusivity in PSP-RS compared with controls, [209][210][211][212][213][214][215][216][217][218] with some evidence for greater rates than in PD, but similar rates of whole-brain and midbrain atrophy as in MSA-P. 212,215 However, cortical and whole-brain rates of atrophy are greater in CBS than in PSP-RS. 209,213 Cerebral blood flow single-photon emission computed tomography studies have demonstrated frontal [219][220][221][222][223][224][225] and, less commonly, thalamic 220 and striatal 222 hypoperfusion in PSP-RS. 221,226 Findings concerning differentiating PSP-RS from other parkinsonian disorders are lacking here, although PSP-RS may show greater frontal hypoperfusion than PD.…”

Sociality and Interaction Envelope Organize Visual Action Representations

“…Brunswick, 1955)? Many prior studies have used the tight link between actions and verbs as a guide, and have measured responses to written verbs or used verbs to guide the selection of pictures or videos of actions (Bedny et al, 2011;Daniele et al, 2013;Leshinskaya & Caramazza, 2014). However, common verbs are not always commonly-seen actions (e.g., "can"), and many commonly-seen actions are not often talked about (e.g., "chopping vegetables").…”