Selective method for identification and quantification ofBifidobacterium animalissubspecieslactisBB-12 (BB-12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB-12 andLactobacillus rhamnosusGG

Poutsiaka, Debra D.; Mahoney, I.; McDermott, L. A.; Stern, Lori; Thorpe, Cheleste M.; Kane, Anne; Baez‐Giangreco, C; McKinney, Julie; Davidson, Lisa; Leyva, Rina; Goldin, Barry R.; Snydman, David R.

doi:10.1111/jam.13436

Cited by 12 publications

(13 citation statements)

References 44 publications

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“…A background of organisms like the ones consumed was detected by the used primer sets. This is not uncommon and has been reported in other fecal detection studies, see, e.g., in [11]. However, after consumption, the levels of these organisms markedly and significantly increased.…”

Section: Discussionsupporting

confidence: 80%

“…The studies that have reported on fecal detection are commonly focusing on a single probiotic strain. Studies that have reported on the fecal recovery of strain combinations have usually focused on strains from different genera, e.g., Bifidobacterium and Lactobacillus [11,12]. Here, we report on the detection of two species from two different genera following their consumption by patients on antibiotic therapy.…”

Section: Discussionmentioning

confidence: 93%

“…The strains included in the current study have all been reported to survive gastrointestinal transit and have been detected in feces: L. acidophilus NCFM [12,13]; L. paracasei Lpc-37 [14]; B. lactis Bl-04 [12], and B. lactis Bi-07 [15]. Moreover, other probiotic strains have been reported to be detected in feces after consumption, e.g., Lactobacillus rhamnosus GG and B. lactis Bb-12 [11]. It is also commonly observed that probiotics can no longer be detected approximately 1 week after consumption has seized [11].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, other probiotic strains have been reported to be detected in feces after consumption, e.g., Lactobacillus rhamnosus GG and B. lactis Bb-12 [11]. It is also commonly observed that probiotics can no longer be detected approximately 1 week after consumption has seized [11].…”

Section: Discussionmentioning

confidence: 99%

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Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment

2020

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The present study aimed to investigate whether probiotic recovery is affected when consumed together with antibiotics. Fecal samples were collected from an earlier antibiotic associated diarrhea, randomized, placebo-controlled study with a product consisting of a combination of Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, and Bifidobacterium lactis Bi-07, B. lactis Bl-04 at equal numbers and at a total dose of 1010 CFU. Fecal samples were collected during the screening visit (T0), i.e., at the time of antibiotic prescription, and then on the last day of the antibiotic treatment (T1) as well as seven days after the subject had stopped taking the antibiotic treatment (T2) and at two weeks after completing antibiotic treatment and one week after probiotic/placebo consumption stopped (T3). Samples were analyzed for the presence of the four administered strains. The study was registered at clinicaltrials.gov as NCT01596829. Detection levels of all four strains were significantly increased from T0 to T1 and returned to baseline level from T2 to T3. There were also significantly more subjects with detectable levels of L. paracasei Lpc-37, B. lactis Bi-07, and B. lactis Bl-04 at T1 and T2 compared to T0 and T3, and compared to placebo. Each of the four strains could be detected in the feces of patients apparently unaffected by the simultaneous consumption of antibiotics.

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment

2020

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“…Suppressing the intestinal infective bacteria, producing some vitamins, anti-cancer and anti-mutation properties, immune system stimulation, reducing blood serum cholesterol, and increasing calcium absorption are some of its other beneficial effects. Bifi dobacterium lactis is the most usable Bifidobacteria in probiotic dairy products (dos Santos Cruxen et al 2017, Gomes and Malcata 1999, Monteagudo-Mera et al 2016, Novak and Katz 2006, Poutsiaka et al 2017.…”

Section: Introductionmentioning

confidence: 99%

Effects of inulin and fat percentage on the viability of Bifi dobacterium lactis Bb12 in chocolate milk

Pourjafar¹,

Ayareh²,

Karim³

et al. 2017

Biosci. Biotech. Res. Comm

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Bifi dobacterium genus has several benefi cial effectsas a probiotic bacterium. It has been demonstrated that Inulin and fat percentage of the probiotic product may modify the viability of this bacterium during storage time. The aim of this study was fi nding the best formulation of the chocolate milk regarding bacterial viability and sensory properties of the fi nal product. Four types of probiotic chocolate milk, with and without inulin in 1% fat samples, with and without inulin in 2% fat samples, were manufactured in duplicate. The count of probiotic cells during 12 days of storage in the refrigerator was assessed. In all samples, the viable cells of Bifi dobacterium lactis increased except 1% fat samples without inulin in which bacterial count decreased (not signifi cantly). The rate of change in the bacterial count was signifi cantly p<0.05 higher in the 2% fat chocolate milk both in with and without inulin samples (0.6 and 0.8) compared with 1% fat samples (0.5 and-0.4). Inulin inoculation had some effects on biochemical and organoleptic changes. After 12 days storage, the acceptability of 2% fat milk with probiotic and inuline was the highest. The results illustrated that the most signifi cant Bifi dobacterium lactis viability was in 2% fat chocolate milk. Adding inulin improved the viability of bacteria in 1% fat milk; however, ithad not any signifi cant effects on the viability of probiotic bacteria in 2% fat milk. In conclusion, 2% fat chocolate milk with inuline could be recommended to be the best group.

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Mechanism of Action and Beneficial Effects of Probiotics in Amateur and Professional Athletes

Nami,

Barghi,

Shahgolzari

et al. 2024

Food Science & Nutrition

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Probiotics are live microorganisms that, when administered in adequate amounts, provide health benefits to the host. According to the International Society of Sports Nutrition (ISSN), probiotic supplementation can optimize the health, performance, and recovery of athletes at all stages of their careers. Recent research suggests that probiotics can improve immune system functions, reduce gastrointestinal distress, and increase gut permeability in athletes. Additionally, probiotics may provide athletes with secondary health benefits that could positively affect athletic performance through enhanced recovery from fatigue, improved immune function, and maintenance of healthy gastrointestinal tract function. The integration of some probiotic strains into athletes' diets and the consumption of multi‐strain compounds may lead to an improvement in performance and can positively affect performance‐related aspects such as fatigue, muscle pain, body composition, and cardiorespiratory fitness. In summary, probiotics can be beneficial for athletes at all stages of their careers, from amateur to professional. This paper reviews the progress of research on the role of probiotic supplementation in improving energy metabolism and immune system functions, reducing gastrointestinal distress, and enhancing recovery from fatigue in athletes at different levels.

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Selective method for identification and quantification ofBifidobacterium animalissubspecieslactisBB-12 (BB-12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB-12 andLactobacillus rhamnosusGG

Abstract: This method will enable more detailed and specific studies of BB-12 in probiotic supplements, including when in combination with LGG.

Cited by 12 publications

References 44 publications

Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment

Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment

Effects of inulin and fat percentage on the viability of Bifi dobacterium lactis Bb12 in chocolate milk

Mechanism of Action and Beneficial Effects of Probiotics in Amateur and Professional Athletes

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