Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups

An efficient regioselective iodination of the Fischer-Borsche ring has been achieved using molecular iodine, in a one-pot synthesis. The acid-, metal-, and oxidant-free conditions of the present method are highly convenient and practical. Furthermore, the one-pot direct iodination process is extended to the concise synthesis of glycozoline, 3-formyl-6-methoxy-carbazole, and 6-methoxy-carbazole-3-methylcarboxylate natural alkaloids. This method has been proven to be tolerant to a broad range of functional groups, with good to excellent yields.

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Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups

Cited by 8 publications

References 46 publications

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I₂

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I₂

A metal-free protocol for direct oxidative de-alkoxycarbonylation of alkyl phenyl acetate by molecular iodine

A One-Pot Direct Iodination of the Fischer–Borsche Ring Using Molecular Iodine and Its Utility in the Synthesis of 6-Oxygenated Carbazole Alkaloids

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Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups

Cited by 8 publications

References 46 publications

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I2

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I2

A metal-free protocol for direct oxidative de-alkoxycarbonylation of alkyl phenyl acetate by molecular iodine

A One-Pot Direct Iodination of the Fischer–Borsche Ring Using Molecular Iodine and Its Utility in the Synthesis of 6-Oxygenated Carbazole Alkaloids

Contact Info

Product

Resources

About

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I₂

A Metal‐Free Iodination of Aryl Ethers and Phenols Using I₂