Selective outpatient management of upper gastrointestinal bleeding in the elderly

Cebollero-Santamaria, Francisco

doi:10.1016/s0002-9270(99)00129-x

Cited by 4 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The varying degrees of hepatic and renal impairment and the potential for a larger pharmacodynamic effect of sedatives in old people can make OTC medicines, even with low doses, harmful. Cebollero-Santamaria et al [42] showed that bleeding from a peptic ulcer was associated with use of NSAIDs in 81% of 84 patients and that 95% had purchased their NSAIDs as a OTC drug. The use of recommended doses of the OTC NSAIDs has a relatively good safety profile compared to prescription NSAIDs.…”

Section: Medication Use In Elderly Patientsmentioning

confidence: 99%

Clinical Pharmacology in Old Persons

Jansen

Brouwers

2012

Scientifica

View full text Add to dashboard Cite

The epidemiological transition, with a rapid increase in the proportion in the global population aged over 65 years from 11% in 2010 to 22% in 2050 and 32% in 2100, represents a challenge for public health. More and more old persons have multimorbidities and are treated with a large number of medicines. In advanced age, the pharmacokinetics and pharmacodynamics of many drugs are altered. In addition, pharmacotherapy may be complicated by difficulties with obtaining drugs or adherence and persistence with drug regimens. Safe and effective pharmacotherapy remains one of the greatest challenges in geriatric medicine. In this paper, the main principles of geriatric pharmacology are presented.

show abstract

Section: Medication Use In Elderly Patientsmentioning

confidence: 99%