“…In recent experiments on amphibia however, histological and electrophysiological evidence revealed that axons from the stump of a foreign nerve appeared to form synapses only at the denervated original end-plates, despite being implanted several millimetres from them (Holder, Mills & Tonge, 1982;Sayers & Tonge, 1982a). In contrast, ectopic synapse formation has been observed in the frog following nerve implantation into the end-plate-free region of a bisected sartorius muscle (Miledi, 1962(Miledi, , 1963Breitschmid & Brenner, 1981).…”