Selective response of antigen‐antibody reactions on chiral surfaces modified with 1,2‐diphenylethylenediamine enantiomers

Zhou, Juan; Wang, Lilan; Qiao, Chunming; Wang, Yonghua; Fu, Yingzi

doi:10.1002/sia.3789

Cited by 6 publications

(2 citation statements)

References 33 publications

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“…In this context, the development of chiral electrode surfaces and sensors based on artificial enzymes or prepared using synthetic materials is very attractive. In the last few years, chiral platinum surfaces, 1 – 5 SAM-modified electrodes, 6 , 7 surface-modified nanoporous opal film electrodes, 8 metals doped with chiral organic molecules, 9 films imprinted with enantiopure templates, 10 – 13 or including a chiral crown ether derivative 14 , a sensitivity-enhanced field-effect chiral sensor hinging on a thiophene-based monomer, 15 and mesoporous chiral metal surfaces 16 were described.…”

Section: Introductionmentioning

confidence: 99%

Inherently chiral electrodes: the tool for chiral voltammetry

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Inherently chiral electrodes: the tool for chiral voltammetry

et al. 2015

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“…In this work, the differential pulse voltammetry technique was used to investigate the electrochemical behavior of hydrochlorothiazide and pyridoxine on an ethylenediamine-modified glassy carbon electrode. The fabricated electrode has good stability and reproducibility [31,32], and the modified version has better electrochemical charateristics [33]. Their overlapping peaks were resolved by chemometrics, which avoided the tedious step of separation and purification, simplified the determination process and realized the simultaneous determination of two components in commercial pharmaceuticals.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Overlapped Electrochemical Signals of Hydrochlorothiazide and Pyridoxine on the Ethylenediamine-Modified Glassy Carbon Electrode by Use of Chemometrics Methods

Zhang¹,

Zhou

Chen

et al. 2019

Molecules

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In this work, the electrochemical behavior of hydrochlorothiazide and pyridoxine on the ethylenediamine-modified glassy carbon electrode were investigated by differential pulse voltammetry. In pH 3.4 Britton-Robinson (B-R) buffer solution, both hydrochlorothiazide and pyridoxine had a pair of sensitive irreversible oxidation peaks, that overlapped in the 1.10 V to 1.20 V potential range. Under the optimum experimental conditions, the peak current was linearly related to hydrochlorothiazide and pyridoxine in the concentration range of 0.10–2.0 μg/mL and 0.02–0.40 μg/mL, respectively. Chemometrics methods, including classical least squares (CLS), principal component regression (PCR) and partial least squares (PLS), were introduced to resolve the overlapped signals and determine the two components in mixtures, which avoided the troublesome steps of separation and purification. Finally, the simultaneous determination of the two components in commercial pharmaceuticals was performed with satisfactory results.

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Biomolecules at Interfaces: Chiral, Naturally

González‐Campo

Amabilino

2013

Biochirality

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Interfaces are a most important environment in natural and synthetic chemistries for a wide variety of processes, such as catalysis, recognition, separation, and so on. Naturally occurring systems have evolved to one handedness and the study of interfaces where biomolecules are located is a potentially revealing pursuit with regard to understanding the reasons and importance of stereochemistry in these environments. Equally, the spontaneous resolution of achiral and chiral compounds at interfaces could lead to explanations regarding the emergence of single handedness in proteins and sugars. Also, the attachment of biomolecules to surfaces leads to systems capable of stereoselective processes which may be useful for the applications mentioned above. The review covers systems ranging from small biomolecules studied under ultrapure conditions in vacuum to protein adsorption to surfaces in solution, and the techniques that can be used to study them.

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Selective response of antigen‐antibody reactions on chiral surfaces modified with 1,2‐diphenylethylenediamine enantiomers

Cited by 6 publications

References 33 publications

Inherently chiral electrodes: the tool for chiral voltammetry

Inherently chiral electrodes: the tool for chiral voltammetry

Analysis of the Overlapped Electrochemical Signals of Hydrochlorothiazide and Pyridoxine on the Ethylenediamine-Modified Glassy Carbon Electrode by Use of Chemometrics Methods

Biomolecules at Interfaces: Chiral, Naturally

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