Selenium: Dietary Sources, Human Nutritional Requirements and Intake Across Populations

Peters, Kristin; Galinn, Sarah E.; Tsuji, Petra A.

doi:10.1007/978-3-319-41283-2_25

Cited by 10 publications

(10 citation statements)

References 65 publications

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“…These variations, particularly in the amount of Se, may be explainable, as has been indicated by other studies, as a result of the difference in maternal intake of Se through food, [18]. This influence through food intake may further be enhanced by the fact that, the micronutrient content of food stuffs varies due to variations in the geochemical environment where the food stuffs are grown [18] [19] [20].…”

Section: Discussionmentioning

confidence: 87%

“…Furthermore, the extent of the consumption of certain foods, within a locality, particularly those that are noted as rich in the said micronutrient, undoubtedly could explain the variations in the amounts of the Se in different areas. These facts have been stated as the reasons for the different recommended national dietary allowable intake of Se in different countries [18]. Although the following was a limitation of this study, which is, food consumption data were not collected and evaluated as part of this study, due to difficulties in obtaining them, it is not uncommon for such data not to be available as part of such a study, as was for the cited WHO study [9].…”

Section: Discussionmentioning

confidence: 97%

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Double Burden of Malnutrition: Toxic Metals in Breast Milk May Limit the Amounts of Micronutrients Available to Infants through Breast Milk

Awua¹,

Boatin²,

Adom³

et al. 2019

FNS

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Background: The amounts of micronutrients in the diets of infants, and the factors that influence them needs to be monitored at the population level in order to avert detrimental developmental defects that impose lifetime-limitations on an infant's regulatory and defense systems. This study therefore, sought to evaluate if increasing levels of the toxic metals, Hg, Pb and Cd in breast milk will result in reducing amounts of the micronutrients Zn, Se and Cu in breast milk. Methods: Breast milk samples of 114 women living in two mining areas (57 women each) in Ghana, whose babies' amounts of breast milk intake at three months postpartum, and amounts of toxic metals had previously been determined in a prospective study, were analyzed for micronutrients by a combination of acid and microwave digestion, and quantifications were by two different modes (hydrogen and helium) of Octapole Reaction System Inductively Coupled Plasma Mass Spectrometer (7500 ce. Agilent), equipped with an ASX-510 Auto-sampler (Cetac). Results: All the breast milk specimen collected contained detectable amounts of Cu, Zn, both at levels less than have been previously reported, and Se. For specimen that did not contain Pb the amount of Se ranged from about 110 to 245 ng/g of milk, however, as the amount of Pb increased, the corresponding highest detected amount of Se reduced steeply, resulting in a right-angle triangle-shaped scatter plot. Similar relationships were observed between other toxic metals and micronutrients studied. A curve fitting regression analysis showed significant qua

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 97%

Double Burden of Malnutrition: Toxic Metals in Breast Milk May Limit the Amounts of Micronutrients Available to Infants through Breast Milk

Awua¹,

Boatin²,

Adom³

et al. 2019

FNS

View full text Add to dashboard Cite

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“…Dietary selenium intake is considered as the key determinant of selenium status. Specifically, meat and other animal products (liver, kidneys), cereals, Allium (onion, garlic) and Brassica (broccoli, cauliflower) species, and yeast contribute significantly to daily selenium intake, with the highest Se content is found in Brazil nuts [14]. However, certain internal factors may also affect dietary Se intake by limiting its bioavailability.…”

Section: Introductionmentioning

confidence: 99%

Selenium and Selenoproteins in Adipose Tissue Physiology and Obesity

et al. 2020

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Selenium (Se) homeostasis is tightly related to carbohydrate and lipid metabolism, but its possible roles in obesity development and in adipocyte metabolism are unclear. The objective of the present study is to review the current data on Se status in obesity and to discuss the interference between Se and selenoprotein metabolism in adipocyte physiology and obesity pathogenesis. The overview and meta-analysis of the studies on blood Se and selenoprotein P (SELENOP) levels, as well as glutathione peroxidase (GPX) activity in obese subjects, have yielded heterogenous and even conflicting results. Laboratory studies demonstrate that Se may modulate preadipocyte proliferation and adipogenic differentiation, and also interfere with insulin signaling, and regulate lipolysis. Knockout models have demonstrated that the selenoprotein machinery, including endoplasmic reticulum-resident selenoproteins together with GPXs and thioredoxin reductases (TXNRDs), are tightly related to adipocyte development and functioning. In conclusion, Se and selenoproteins appear to play an essential role in adipose tissue physiology, although human data are inconsistent. Taken together, these findings do not support the utility of Se supplementation to prevent or alleviate obesity in humans. Further human and laboratory studies are required to elucidate associations between Se metabolism and obesity.

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“…Selenium (Se) is an essential trace element for mammals, and has important physiological functions such as antioxidation, anticarcinogenic effects, and immunity stimulation (Fairweather-Tait et al, 2011 ). Selenium is found ubiquitously but is geographically variable in the environment, and is transferred through the geochemical cycle rock-soil-water-plants-mammals (Peters et al, 2016 ). The daily intake of Se varies geographically, in the world, 0.5–1 billion people have a Se intake below the recommended 55 μg day −1 and have been estimated to be Se-deficient, including the people living in south island of New Zealand, and parts of China and Europe (Combs Jr, 2001 ; Rayman, 2004 ; Pappas et al, 2008 ; Lv et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Absorption and Bio-Transformation of Selenium Nanoparticles by Wheat Seedlings (Triticum aestivum L.)

et al. 2018

Front. Plant Sci.

117

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Elemental selenium is one of the dominant selenium species in soil, but the mechanism of its uptake by plants is still unclear. In this study, nanoparticles of elemental selenium (SeNPs) with different sizes were prepared, and their uptake and transformation in wheat (Triticum aestivum L.) were analyzed in hydroponic experiments by HPLC-ICP-MS. We found that the SeNPs can be absorbed by wheat seedlings, and the process is energy independent. The addition of aquaporins inhibitor caused 92.5 and 93.4% inhibition of chemosynthesized SeNPs (CheSeNPs) and biosynthesized SeNPs (BioSeNPs) absorption by wheat roots, respectively. The 40 nm SeNPs uptake by wheat roots was 1.8-fold and 2.2-fold higher than that of 140 and 240 nm, respectively. The rate of SeNPs uptake in wheat was much slower than that of selenite [Se (IV)], and CheSeNPs were more efficiently absorbed than BioSeNPs. The SeNPs were rapidly oxidized to Se (IV) and converted to organic forms [selenocystine (SeCys2), se-methyl-selenocysteine (MeSeCys), and selenomethionine (SeMet)] after they were absorbed by wheat roots. Additionally, we demonstrated that the aquaporin function in some way is related to the absorption of SeNPs. The particle size and synthesis method of the SeNPs affected their uptake rates by plants. Taken together, our results provide a deep understanding of the SeNPs uptake mechanism in plants.

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Selenium: Dietary Sources, Human Nutritional Requirements and Intake Across Populations

Cited by 10 publications

References 65 publications

Double Burden of Malnutrition: Toxic Metals in Breast Milk May Limit the Amounts of Micronutrients Available to Infants through Breast Milk

Double Burden of Malnutrition: Toxic Metals in Breast Milk May Limit the Amounts of Micronutrients Available to Infants through Breast Milk

Selenium and Selenoproteins in Adipose Tissue Physiology and Obesity

Absorption and Bio-Transformation of Selenium Nanoparticles by Wheat Seedlings (Triticum aestivum L.)

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