Selenium sulfide in tinea versicolor: Blood and urine levels

Sánchez, Jorge; Torres, Víctor

doi:10.1016/s0190-9622(84)70156-3

Cited by 15 publications

(3 citation statements)

References 17 publications

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“…Washing hair twice weekly with selenium sulfide along with oral griseofulvin have demonstrated superiority in treating tinea capitis to griseofulvin alone [67, 69]. Unlike systemic antifungals, it is used topically and does not result in a significant systemic absorption [70]. Therefore, it is a good option for close contacts of infected individuals and asymptomatic carriers [1, 29].…”

Section: Adjuvant Therapymentioning

confidence: 99%

Treatment of Tinea Capitis

Alkeswani

Cantrell²,

Elewski

2019

Skin Appendage Disord

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Tinea capitis is a common fungal infection of the hair of the scalp affecting predominately prepubertal children. In the US, griseofulvin has been considered a first-line therapy agent for tinea capitis since the 1960s. However, it has been falling out of favor due to significant treatment failure, high cost, and long duration of treatment. Other antifungal agents have been researched as an alternative to griseofulvin. This paper will review the relevant pharmacologic properties, dosing, cost, efficacy, and adverse events profile for griseofulvin, terbinafine, itraconazole, fluconazole, and some adjuvant therapy options such as selenium sulfide shampoos and topical ketoconazole.

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Section: Adjuvant Therapymentioning

confidence: 99%

Treatment of Tinea Capitis

Alkeswani

Cantrell²,

Elewski

2019

Skin Appendage Disord

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“…Hair loss has been described with selenium toxicity related to occupational selenium exposure (21) but has not been reported with topical application in several large studies (19,22). Daily application of selenium sulfide lotion to the entire cutaneous surface daily for 1 week did not affect blood and urine selenium levels, suggesting that systemic absorption is limited when used topically (23). Cases of allergic contact dermatitis have been documented and verified with patch testing (24).…”

Section: Discussionmentioning

confidence: 99%

Scalp Discoloration from Selenium Sulfide Shampoo: A Case Series and Review of the Literature

Gilbertson

Jarrett

Bayliss

et al. 2011

Pediatric Dermatology

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We describe six patients who developed orange to red-brown scalp discoloration after application of selenium sulfide-containing shampoos. This phenomenon has been described only once previously. In all of the cases, the discoloration resolved shortly after discontinuing the selenium sulfide. Lightly swabbing with isopropyl alcohol facilitated removal of the discoloration. This simple technique serves as a painless diagnostic method, which may prevent unnecessary evaluation with a biopsy.

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“…194 Selenium sulfide, available as a shampoo, lotion and cream in 1-2.5% concentrations, is safe and effective in the treatment of tinea versicolor. 147,[195][196][197] Studies have shown that the success rate of selenium sulfide shampoo in the treatment of tinea versicolor is comparable to that of topical bifonazole and econazole. 198,199 Advantages of selenium sulfide include over-the-counter availability, low cost and convenient application.…”

Section: Non-specific Topical Antifungal Agentsmentioning

confidence: 99%

Tinea versicolor: an updated review

Leung¹,

Barankin²,

Lam³

et al. 2022

DIC

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A search was conducted in July 2022 in PubMed Clinical Queries using the key terms "tinea versicolor" OR "pityriasis versicolor". The search strategy included all clinical trials (including open trials, non-randomized controlled trials and randomized controlled trials), observational studies and reviews (including narrative reviews and meta-analyses) published within the past 10 years. Only papers published in the English literature were included in this review. The information retrieved from the search was used in the compilation of this article. Review AetiopathogenesisTinea versicolor is caused by dimorphic lipophilic and lipid-dependent yeasts in the genus Malassezia (formerly known as Pityrosporum) species, notably Malassezia globosa (M. globose), M. furfur and M. sympodialis. [2][3][4][5][6][7][8][9][10][11][12] Other species that have been implicated include M. restricta, M. obtuse, M. slooffiae, M. pachydermatis and M. japonica. [13][14][15][16] These yeasts are normal commensals on the skin surface. 17,18 Skin colonization increases with age; 25% of children and almost 100% of adults are affected. 19 Tinea versicolor occurs when the saprophytic yeast or budding form of the organism converts to the pathogenic hyphal or mycelial form. The fungal infection is localized to the stratum corneum. Predisposing factors for the conversion include a hot and humid environment, hyperhidrosis, application of oily lotion or cream to the skin, wearing of masks, excessive lipid-containing sebaceous secretions, malnutrition, poor general health, use of oral contraceptives, pregnancy, diabetes mellitus, use of topical or systemic corticosteroids, Cushing disease, Helicobacter pylori infection, immunodeficiency and genetic predisposition. [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] A recent study showed oxidative stress has no role in the pathogenesis of tinea versicolor. 29

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Selenium sulfide in tinea versicolor: Blood and urine levels

Cited by 15 publications

References 17 publications

Treatment of Tinea Capitis

Treatment of Tinea Capitis

Scalp Discoloration from Selenium Sulfide Shampoo: A Case Series and Review of the Literature

Tinea versicolor: an updated review

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