Selenium, zinc and copper in the Polish diet

Jabłońska, Ewa; Gromadzińska, Jolanta; Kłos, Anna; Bertrandt, Jerzy; Skibniewska, Krystyna A.; Daragó, Adam; Wąsowicz, Wojciech

doi:10.1016/j.jfca.2013.05.016

Cited by 30 publications

(18 citation statements)

References 21 publications

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“…The Mn levels determined in pork cuts (0.064-0.124 mg kg -1 ) were more than two to almost fivefold higher than those reported by Tomović et al [9] in pigs from different genetic lines (Mn: 0.025 ± 0.004 mg/kg) but lower than levels given Batista et al [2] in pork (0.214 mg kg -1 ). Se levels in the analysed pork cuts (0.091-0.209 mg kg -1 ) were higher than reported by Jablonska et al [10] in 24 selected meat (ranging from 0.007 to 0.161 mg kg -1 ), and Fajt et al [11], in pork samples from different herds in Czech Republic (0.087 mg kg -1 ). On the other hand, Se levels in pork reported by Batista et al [2], (0.461 mg kg -1 ) were higher than those obtained in our study.…”

Section: Resultscontrasting

confidence: 62%

Distribution of manganese and selenium in four different pork cuts commercially available in the Serbian market

Đinović-Stojanović

Nikolić

Janković

et al. 2017

IOP Conf. Ser.: Earth Environ. Sci.

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Abstract. This study aimed to provide information on levels of Mn and Se in four different pork cuts (loin, neck, hind leg and shoulder) commercially available on the Serbian market, with a view to providing information on dietary intakes of metals associated with the consumption of these meat cuts. In total, for 50 pork cuts, the levels of Mn and Se were determined by inductively-coupled plasma mass spectrometry (ICP-MS).

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Section: Resultscontrasting

confidence: 62%

Distribution of manganese and selenium in four different pork cuts commercially available in the Serbian market

Đinović-Stojanović

Nikolić

Janković

et al. 2017

IOP Conf. Ser.: Earth Environ. Sci.

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“…Nobody declared smoking tobacco and taking Se containing supplements during the study. Dietary questionnaires concerned frequency of consumption of food products which contain the highest Se content in the Polish diet (according to our previous study [26]). As shown in supplementary figures (Figure S2), the overall consumption frequency of eggs, fish, and nuts was similar during 6-week period of supplementation as compared to the washout.…”

Section: Resultsmentioning

confidence: 99%

“…Thus, the aim of this study was to analyze the potential influence of two functional single-nucleotide polymorphisms (SNPs), present within the coding region of two selenoprotein genes: GPX1 rs1050450 (Pro198Leu) and SEPP1 rs3877899 (Ala234Thr), on the multilevel biological response to Se supplementation. Due to a low dietary intake of Se in the Polish population [26], individuals from Poland who constituted the study group seemed to be relevant to investigate the possible gene–selenium interactions. Biomarkers of relevance included markers of Se status (plasma Se and Sepp1 concentrations), markers of oxidative stress (activity of antioxidant enzymes in plasma or erythrocytes, plasma lipid peroxidation, oxidative burst in the whole-blood leukocytes), DNA strand breaks, DNA oxidation, and mRNA expression of selected encoding selenoproteins or related genes ( GPX1 , GPX4 , TRXR1 , SEP15 , SEPP1 , SELS , SELW , SBP2 ).…”

Section: Introductionmentioning

confidence: 99%

DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism

et al. 2015

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PurposeSelenium, both essential and toxic element, is considered to protect against cancer, though human supplementation trials have generated many inconsistent data. Genetic background may partially explain a great variability of the studies related to selenium and human health. The aim of this study was to assess whether functional polymorphisms within two selenoprotein-encoding genes modify the response to selenium at the level of oxidative stress, DNA damage, and mRNA expression, especially in the individuals with a relatively low selenium status.MethodsThe trial involved 95 non-smoking individuals, stratified according to GPX1 rs1050450 and SEPP1 rs3877899 genotypes, and supplemented with selenium yeast (200 µg) for 6 weeks. Blood was collected at four time points, including 4 weeks of washout.ResultsAfter genotype stratification, the effect of GPX1 rs1050450 on lower GPx1 activity responsiveness was confirmed; however, in terms of DNA damage, we failed to indicate that individuals homozygous for variant allele may especially benefit from the increased selenium intake. Surprisingly, considering gene and time interaction, GPX1 polymorphism was observed to modify the level of DNA strand breaks during washout, showing a significant increase in GPX1 wild-type homozygotes. Regardless of the genotype, selenium supplementation was associated with a selectively suppressed selenoprotein mRNA expression and inconsistent changes in oxidative stress response, indicating for overlapped, antioxidant, and prooxidant effects. Intriguingly, DNA damage was not influenced by supplementation, but it was significantly increased during washout.ConclusionsThese results point to an unclear relationship between selenium, genotype, and DNA damage.Electronic supplementary materialThe online version of this article (doi:10.1007/s00394-015-1118-4) contains supplementary material, which is available to authorized users.

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“…When compared to Se intakes in USA, Japan, Canada and Venezuela (reaching even 300 lg day À1 ), European values are much lower (Jablonska et al, 2013). The results obtained by Wasowicz, Gromadzinska, Rydzynski, and Tomczak (2003) showed that Se concentration in the blood of the inhabitants of Poland depends on the region of the country.…”

Section: Introductionmentioning

confidence: 91%