Self-adaptive cardiac optogenetics device based on negative stretching-resistive strain sensor

Hong, Wen; Jiang, Chunpeng; Qin, Mu; Song, Ziliang; Ji, Peng; Wang, Longchun; Tu, Kejun; Liu, Lu; Guo, Zhejun; Wang, Xiaolin; Liu, Jingquan

doi:10.1126/sciadv.abj4273

Cited by 29 publications

(16 citation statements)

References 49 publications

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Section: D Free-form Displaysmentioning

confidence: 99%

“…Hong et al demonstrated an optogenetics therapy based on a closed-loop system consisting of a strain sensor array for heart rate monitoring, a processing circuit, and LEDs with self-adaptive light intensity control (Fig. 8c ) 74 . The strain sensor array wrapping around the heart could detect negative resistance variation over a wide strain range.…”

Section: D Free-form Displaysmentioning

confidence: 99%

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Fabrication of practical deformable displays: advances and challenges

Kim

Lee

et al. 2023

Light Sci Appl

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Display form factors such as size and shape have been conventionally determined in consideration of usability and portability. The recent trends requiring wearability and convergence of various smart devices demand innovations in display form factors to realize deformability and large screens. Expandable displays that are foldable, multi-foldable, slidable, or rollable have been commercialized or on the edge of product launches. Beyond such two-dimensional (2D) expansion of displays, efforts have been made to develop three dimensional (3D) free-form displays that can be stretched and crumpled for use in realistic tactile sensation, artificial skin for robots, and on-skin or implantable displays. This review article analyzes the current state of the 2D and 3D deformable displays and discusses the technological challenges to be achieved for industrial commercialization.

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Section: D Free-form Displaysmentioning

confidence: 99%

Section: D Free-form Displaysmentioning

confidence: 99%

Fabrication of practical deformable displays: advances and challenges

Kim

Lee

et al. 2023

Light Sci Appl

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“…Recently, flexible strain sensors have attracted much attention for their excellent performance in healthcare, − soft machines, − human–computer interfaces, − etc. These application scenarios put forward higher requirements for the design and manufacture of sensors, which should have high flexibility, stretchability, and excellent sensitivity to detect a wide range of strains, often depending on the substrate and sensitive material.…”

Section: Introductionmentioning

confidence: 99%

Understanding the Origin of Tensile Response in a Graphene Textile Strain Sensor with Negative Differential Resistance

et al. 2022

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The flexible strain sensors based on the textile substrate have natural flexibility, high sensitivity, and wide-range tensile response. However, the textile’s complex and anisotropic substructure leads to a negative differential resistance (NDR) response, lacking a deeper understanding of the mechanism. Therefore, we examined a graphene textile strain sensor with a conspicuous NDR tensile response, providing a requisite research platform for mechanism investigation. The pioneering measurement of single fiber bundles confirmed the existence of the NDR effect on the subgeometry scale. Based on the in situ characterization of tensile morphology and measurement, we conducted quantitative behavior analyses to reveal the origin of tensile electrical responses in the full range comprehensively. The results showed that the dominant factor in generating the NDR effect is the relative displacement of fibers within the textile bundles. Based on the neural spiking-like tensile response, we further demonstrated the application potential of the textile strain sensor in threshold detection and near-sensor signal processing. The proposed NDR behavior model would provide a reference for the design and application of wearable intelligent textiles.

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“…A myriad of strain sensors based on various sensing mechanisms including resistance [6], capacitance [7,8], piezoresistive [9], piezoelectric [10], and inductance [11,12] have been developed. To meet the growing demand for practical medical applications in variable harsh conditions, stretching-resistive strain sensors have been widely used due to their ease of manufacturing and integration, costeffectiveness, and scalability [13][14][15][16]. In general, resistive strain sensors turn strain to raising resistance as a result of gradual breaking of conductive path.…”

Section: Introductionmentioning

confidence: 99%

“…At present, crack-based resistive sensors have been widely fabricated to achieve high gauge factor (GF), which contributes to improvement of the sensitivity [17,18]. It is worth noting that resistor thermal noise, which is positively associated with resistance, also significantly influences the detection output [13,19]. Therefore, highly conductive materials such as metals, liquid metal, graphene, carbon nanotubes (CNTs), metallic nanoplates and nanowires (NWs) are often used to construct conductive materials [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Stress-deconcentrated ultrasensitive strain sensor with hydrogen-bonding-tuned fracture resilience for robust biomechanical monitoring

et al. 2022

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Recently, rapid advances in flexible strain sensors have broadened their application scenario in monitoring of various mechanophysiological signals. Among various strain sensors, the crack-based strain sensors have drawn increasing attention in monitoring subtle mechanical deformation due to their high sensitivity. However, early generation and rapid propagation of cracks in the conductive sensing layer result in a narrow working range, limiting their application in monitoring large biomechanical signals. Herein, we developed a stress-deconcentrated ultrasensitive strain (SDUS) sensor with ultrahigh sensitivity (gauge factor up to 2.3 × 10 6 ) and a wide working range (0%-50%) via incorporating notch-insensitive elastic substrate and microcrack-tunable conductive layer. Furthermore, the highly elastic amine-based polymer-modified polydimethylsiloxane substrate without obvious hysteresis endows our SDUS sensor with a rapid response time (2.33 ms) to external stimuli. The accurate detection of the radial pulse, joint motion, and vocal cord vibration proves the capability of SDUS sensor for healthcare monitoring and human-machine communications.

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Self-adaptive cardiac optogenetics device based on negative stretching-resistive strain sensor

Abstract: A closed-loop and self-adaptive cardiac optogenetics is realized by a negative stretching-resistive strain sensor.

Cited by 29 publications

References 49 publications

Fabrication of practical deformable displays: advances and challenges

Fabrication of practical deformable displays: advances and challenges

Understanding the Origin of Tensile Response in a Graphene Textile Strain Sensor with Negative Differential Resistance

Stress-deconcentrated ultrasensitive strain sensor with hydrogen-bonding-tuned fracture resilience for robust biomechanical monitoring

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