Self‐ and Directed‐Assembly of Metallic and Nonmetallic Fluorophors: Considerations into Graphene and Graphene Oxides for Sensing and Imaging Applications

Calatayud, David G.; Cortezon‐Tamarit, Fernando; Mao, Boyang; Mirabello, Vincenzo; Pascu, Sofia I.

doi:10.1002/9781119468455.ch83

Cited by 2 publications

(4 citation statements)

References 190 publications

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“…Aspects of medical imaging techniques and the development of relevant chemistry-focused tools constitute one of the main research frontiers that we were interested in, and contributed through doctoral thesis programs and thematic reviews over the years: the most recent advances in this field, with an overview of the work published in the past decade, are the focus of this review. ,− …”

Section: Molecular Imaging Techniques Addressed By Nanoparticulate Toolsmentioning

confidence: 99%

“…A very summary overview of medical imaging approaches, taken from the perspective of the interface between physical and life sciences is highlighted below to set the scene of this review at the interface between disciplines. ,− …”

Section: Molecular Imaging Techniques Addressed By Nanoparticulate Toolsmentioning

confidence: 99%

“…Over the years, significant efforts have been employed in addressing challenges in hypoxia targeting with small molecular tracers, and we, and others, have highlighted the unmet research needs in the field over the years. ,− …”

Section: Radiolabeled Nanoparticle-based Agents For Tracing Hypoxiamentioning

confidence: 99%

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Functional Diversity in Radiolabeled Nanoceramics and Related Biomaterials for the Multimodal Imaging of Tumors

Calatayud

Lledos

Casarsa

et al. 2023

ACS Bio Med Chem Au

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Nanotechnology advances have the potential to assist toward the earlier detection of diseases, giving increased accuracy for diagnosis and helping to personalize treatments, especially in the case of noncommunicative diseases (NCDs) such as cancer. The main advantage of nanoparticles, the scaffolds underpinning nanomedicine, is their potential to present multifunctionality: synthetic nanoplatforms for nanomedicines can be tailored to support a range of biomedical imaging modalities of relevance for clinical practice, such as, for example, optical imaging, computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), and positron emission tomography (PET). A single nanoparticle has the potential to incorporate myriads of contrast agent units or imaging tracers, encapsulate, and/or be conjugated to different combinations of imaging tags, thus providing the means for multimodality diagnostic methods. These arrangements have been shown to provide significant improvements to the signal-to-noise ratios that may be obtained by molecular imaging techniques, for example, in PET diagnostic imaging with nanomaterials versus the cases when molecular species are involved as radiotracers. We surveyed some of the main discoveries in the simultaneous incorporation of nanoparticulate materials and imaging agents within highly kinetically stable radio-nanomaterials as potential tracers with (pre)clinical potential. Diversity in function and new developments toward synthesis, radiolabeling, and microscopy investigations are explored, and preclinical applications in molecular imaging are highlighted. The emphasis is on the biocompatible materials at the forefront of the main preclinical developments, e.g., nanoceramics and liposome-based constructs, which have driven the evolution of diagnostic radio-nanomedicines over the past decade.

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Section: Molecular Imaging Techniques Addressed By Nanoparticulate Toolsmentioning

confidence: 99%

Section: Molecular Imaging Techniques Addressed By Nanoparticulate Toolsmentioning

confidence: 99%

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Functional Diversity in Radiolabeled Nanoceramics and Related Biomaterials for the Multimodal Imaging of Tumors

Calatayud

Lledos

Casarsa

et al. 2023

ACS Bio Med Chem Au

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“…We reported recently on the lab scale preparation of new functional porphyrins modified in both meso-and β-position and metalled to obtain a more tuneable UV-vis absorption. Such functional porphyrins have been deemed challenging to synthesis on a lab scale previously; however, in our recent studies, we isolated these and studied their interactions with carbon nanomaterials (Mao et al, 2016;Tyson et al, 2016a;Mao et al, 2017;Calatayud et al, 2019;Mao et al, 2019;Owen et al, 2020).…”

Section: Graphene and Graphene Oxide As Materials Scaffolds In Photovoltaicmentioning

confidence: 99%

Self-Assembled Materials Incorporating Functional Porphyrins and Carbon Nanoplatforms as Building Blocks for Photovoltaic Energy Applications

et al. 2021

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Self‐ and Directed‐Assembly of Metallic and Nonmetallic Fluorophors: Considerations into Graphene and Graphene Oxides for Sensing and Imaging Applications

Cited by 2 publications

References 190 publications

Functional Diversity in Radiolabeled Nanoceramics and Related Biomaterials for the Multimodal Imaging of Tumors

Functional Diversity in Radiolabeled Nanoceramics and Related Biomaterials for the Multimodal Imaging of Tumors

Self-Assembled Materials Incorporating Functional Porphyrins and Carbon Nanoplatforms as Building Blocks for Photovoltaic Energy Applications

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