Self- and Informant Ratings of Personality in Mild Cognitive Impairment, Reviewed

Abstract

Aims: To examine the degree of agreement between self- and informant ratings of personality in relation to cognitive function in patients with mild cognitive impairment (MCI), subjective cognitive impairment (SCI) and healthy controls (HC). Methods: Thirty-two patients and informants with MCI, 23 with SCI and 22 HC completed the Swedish universities Scales of Personality (SSP). Correlations and incongruence between self- and informant ratings were calculated. The Mini Mental State Examination (MMSE) was used to assess cognitive function. Results: The correlations between self- and informant ratings were fair-to-moderate on a majority of SSP scales and significant in 44%. The incongruence between patients and informants was significantly larger in MCI than in HC across SSP scales. There was a significant negative correlation between the incongruence index and the MMSE for all subjects. Conclusions: Self-informant agreement on ratings of patients’ personality was reasonable. Incongruence between patients and their informants was associated with MCI but not SCI or HC. Disagreement between patients and informants indicates cognitive impairment.

Correlates of Subjective and Mild Cognitive Impairment: Depressive Symptoms and CSF Biomarkers

“…These results suggest that patients with incipient cognitive difficulties (SCI), not satisfying the clinical criteria for MCI, assess their cognitive abilities more correctly, while patients with MCI tend to underestimate their cognitive difficulties. Similarly, disagreement between patients and their informants was associated with MCI but not SCI in another recent study [62]. …”

Medial Temporal Lobe Atrophy and Depressive Symptoms in Elderly Patients With and Without Alzheimer Disease

“…Progression of AD symptomatology occurs on a spectrum from preclinical-asymptomatic AD, symptomatic-prodromal AD to clinically manifest AD 48 Improved diagnostic techniques and criteria allow a better clinical diagnoses of SCI, MCI and AD. However, a diagnosis of definite AD can only be established post-mortem 34 SCI is a heterogeneous clinical entity, being present in different other medical condition or as a side effect of treatment and it can be influenced by personal traits 49,50 . Nowadays there are many international efforts to identify SCI due to AD.…”

“…Our findings support the results reported in study I and II, that suggest that patients with depressive symptoms seek medical help in earlier stages of the disease. Depressive symptoms can lead to memory complains and personality changes that are observed in early stages of MCI and dementia50 . However, fewer patients with depressive symptoms or using antidepressants were followed up, and this may have influenced the findings.The present studies have a number of methodological limitations.…”

A review of amnestic MCI screening in east/southeast Asian older adults with low education: implications for early informant-clinician collaboration

“…Informants are especially important for persons with low education (Narasimhalu et al, 2008). They might be unaware of their cognitive changes (Ausen et al, 2011); or might be culturally socialized to assess their own cognitive abilities differently (Wong et al, 2006). In such situations, these older adults would be most prone to receive medical attention for their declined cognition much later (Roe et al, 2008;Ng et al, 2010).…”