Self and schizophrenia: current status and diagnostic implications

Parnas, Josef; Zandersen, Maja

doi:10.1002/wps.20528

Cited by 28 publications

(20 citation statements)

References 12 publications

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“…The concept of self-disorders is also relevant to the demarcation of these disorders. Self-disorders encompass disturbances of the basic structure of subjectivity or the first-person perspective, i.e., the experience of existing as a unified, embodied, temporally stable and demarcated subject [57,63]. A considerably body of empirical studies from different groups have shown that disturbances of this level of basic selfhood hyper-aggregate in schizophrenia-spectrum disorders, including SPD, as opposed to bipolar disorder, borderline personality disorder and other psychiatric disorders (for a review, see [59]).…”

Section: Introductionmentioning

confidence: 99%

Schizophrenia-spectrum psychopathology in obsessive–compulsive disorder: an empirical study

Rasmussen

Nordgaard

Parnas

2019

Eur Arch Psychiatry Clin Neurosci

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The differential diagnosis of obsessive-compulsive disorder (OCD) and schizophrenia-spectrum disorders can be difficult. In the current diagnostic criteria, basic concepts such as obsession and delusion overlap. This study examined lifetime schizophrenia-spectrum psychopathology, including subtle schizotypal symptomatology and subjective anomalies such as self-disorders, in a sample diagnosed with OCD in a specialized setting. The study also examined the differential diagnostic potential of the classic psychopathological notions of true obsession ('with resistance') and pseudo-obsession. The study involved 42 outpatients diagnosed with OCD at two clinics specialized in the treatment of OCD. The patients underwent semi-structured, narrative interviews assessing a comprehensive battery of psychopathological instruments. The final lifetime research-diagnosis was based on a consensus between a senior clinical psychiatrist and an experienced research clinician. The study found that 29% of the patients fulfilled criteria of schizophrenia or another non-affective psychosis as main, lifetime DSM-5 research-diagnosis. Another 33% received a research-diagnosis of schizotypal personality disorder, 10% a research-diagnosis of major depression and 29% a main research-diagnosis of OCD. Self-disorders aggregated in the schizophrenia-spectrum groups. True obsessions had a specificity of 93% and a sensitivity of 58% for a main diagnosis of OCD. In conclusion, a high proportion of clinically diagnosed OCD patients fulfilled diagnostic criteria of a schizophrenia-spectrum disorder. The conspicuous obsessive-compulsive symptomatology may have resulted in a disregard of psychotic symptoms and other psychopathology. Furthermore, the differentiation of obsessions from related psychopathological phenomena is insufficient and a conceptual and empirical effort in this domain is required in the future.

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Section: Introductionmentioning

confidence: 99%

Schizophrenia-spectrum psychopathology in obsessive–compulsive disorder: an empirical study

Rasmussen

Nordgaard

Parnas

2019

Eur Arch Psychiatry Clin Neurosci

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“…The construct of basic (core, minimal) self disturbance has emerged in recent years as a possible key phenotypic marker of the schizophrenia spectrum.…”

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confidence: 99%

Testing a neurophenomenological model of basic self disturbance in early psychosis

et al. 2019

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“…In a detailed historical, conceptual and empirical review, we have argued that the division of the borderline group into BPD and SPD was not entirely justified, and that the BPD category today is overinclusive and both clinically and conceptually difficult to differentiate from the schizophrenia spectrum disorders. In a separate study, we have pointed out that the BPD criteria of “identity disturbance” and “chronic feelings of emptiness” refer to multi‐layered phenomena which in their basic aspects of structural change of experience were both originally ascribed to the schizophrenia spectrum.…”

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confidence: 99%

Borderline personality disorder or a disorder within the schizophrenia spectrum? A psychopathological study

Zandersen

Parnas

2019

World Psychiatry

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Self and schizophrenia: current status and diagnostic implications

Cited by 28 publications

References 12 publications

Schizophrenia-spectrum psychopathology in obsessive–compulsive disorder: an empirical study

Schizophrenia-spectrum psychopathology in obsessive–compulsive disorder: an empirical study

Testing a neurophenomenological model of basic self disturbance in early psychosis

Borderline personality disorder or a disorder within the schizophrenia spectrum? A psychopathological study

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