2024
DOI: 10.1021/acsami.4c14686
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Self-assembled Arginine–Glycine–Aspartic Acid Mimic Peptide Hydrogels as Multifunctional Biomaterials for Wound Healing

Zeba Ahmadi,
Diksha Jha,
Santosh Yadav
et al.

Abstract: Clinical management of nonhealing ulcers requires advanced materials that can enhance wound closure rates without relying on the release of drugs or other growth factors to obviate systemic deleterious side effects. In our previous work, we synthesized an integrin-binding cell adhesive M NH2 {Fmoc-FFβAR(K)βA-NH 2 consisting of an RGD mimic, [R(K)], with an amide terminus}, M OH {Fmoc-FFβAR(K)βA-OH consisting of an RGD mimic, [R(K)], with acid terminus}, and M R (Fmoc-FFβARGDβA-NH 2 consisting of an RGD peptide… Show more

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