Self-assembled CeVO₄/Au heterojunction nanocrystals for photothermal/photoacoustic bimodal imaging-guided phototherapy

Abstract

CeVO4/Au NCs can be used as an effective photothermal/photoacoustic bimodal imaging-guided theranostic anticancer agent for near-infrared (NIR) light-mediated photothermal/photodynamic therapy.

Biomedical applications of cerium vanadate nanoparticles: a review

“…All indices were within normal limits and trended closely toward those of the control group, indicating there was no inflammatory response or necrocytosis in the liver or kidneys. 78 Jian et al also discovered no toxicity of CeO 2 NPs in vivo or in vitro when testing their biocompatibility and cytotoxicity. Toxicity typically manifests itself in the wake of a very potent treatment.…”

“…However, they absorb near-infrared (NIR) light poorly, limiting their utility for environmental remediation and medical applications. In order to resolve this issue, scientists synthesized CeVO 4 /Ag nanohybrids using a 78 The incorporation of metal ions into cerium vanadate nanoparticles (CeVO 4 NPs) signifies an innovative and critical area in the field of nanomaterial design. Gold nanoparticles, which are widely recognized for their unique physicochemical properties and biocompatibility, add an additional level of intricacy to the CeVO 4 system.…”

“…4). 78 In addition, a study published by Li et al found that ultra-small vanadate prodrug NPs, which include CeVO 4 NPs, can specifically inhibit Na/K-ATPase in cancer cells, leading to apoptosis. 93 It is important to note that while CeVO 4 NPs have shown potential as anticancer agents, their biosafety still needs to be carefully evaluated before clinical application.…”

“…Thus, CeVO 4 /Au NCs may function as theranostic anticancer agents when combined with photothermal and photodynamic treatments based on NIR-light. 78 The incorporation of metal ions into cerium vanadate nanoparticles (CeVO 4 NPs) signifies an innovative and critical area in the field of nanomaterial design. Gold nanoparticles, which are widely recognized for their unique physicochemical properties and biocompatibility, add an additional level of intricacy to the CeVO 4 system.…”

Vanadium-based nanomaterials for cancer diagnosis and treatment

“…The metal vanadates are not good PTA candidates because of their relatively wide band gaps [109,110]. To improve the light absorption in the NIR window of vanadate-based nanomaterials, the integration of metal nanomaterials into vanadate-based nanomaterials is considered to be an effective approach [87,91,111]. Some metal nanomaterials, such as Au, Ag and Cu nanomaterials, can effectively absorb light energy in the NIR region and convert it to heat through the localized surface plasmon resonance effect [112].…”