Self-assembled monolayers of rigid thiols

Ulman, Abraham; Kang, Jung F.; Shnidman, Yitzhak; Liao, Sheng; Jordan, Rainer; Choi, Gun Young; Zaccaro, Julien; Myerson, Allan S.; Rafailovich, Miriam; Sokolov, Jonathan; Fleischer, Cathy

doi:10.1016/s1389-0352(00)00013-1

Cited by 83 publications

(72 citation statements)

References 56 publications

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“…86,[90][91][92] The physicochemical properties of the monolayers are determined by the identity of the terminal functionality of the adsorbate, 93,94 as demonstrated, for example, by its effect on wetting. [95][96][97][98] Recently, SAMs have also been used as model systems for the design of biosensors 67,[99][100][101][102] and nanoscale switchable surfaces.…”

Section: B Controlled Adsorption Of Proteins On Selfassembled Monolamentioning

confidence: 99%

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

et al. 2009

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This review focuses on the surface modification of substrates with self-assembled monolayers (SAMs) and polymer brushes to tailor interactions with biological systems and to thereby enhance their performance in bioapplications. Surface modification of biomedical implants promotes improved biocompatibility and enhanced implant integration with the host. While SAMs of alkanethiols on gold substrates successfully prevent nonspecific protein adsorption in vitro and can further be modified to tether ligands to control in vitro cell adhesion, extracellular matrix assembly, and cellular differentiation, this model system suffers from lack of stability in vivo. To overcome this limitation, highly tuned polymer brushes have been used as more robust coatings on a greater variety of biologically relevant substrates, including titanium, the current orthopedic clinical standard. In order to improve implant-bone integration, the authors modified titanium implants with a robust SAM on which surface-initiated atom transfer radical polymerization was performed, yielding oligo(ethylene glycol) methacrylate brushes. These brushes afforded the ability to tether bioactive ligands, which effectively promoted bone cell differentiation in vitro and supported significantly better in vivo functional implant integration.

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Section: B Controlled Adsorption Of Proteins On Selfassembled Monolamentioning

confidence: 99%

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

et al. 2009

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“…Among the most employed ligands for metal nanoparticles, thiols [39,[322][323][324][325][326][327][328] have to be mentioned, whereas metal oxides NP can be conveniently derivatised by carboxylates or, even stronger, by multifunctional ligands such as dopamine-derivatives and cathecols [280,283,292,[329][330][331]. A further distinction can be carried out accordingly to the chemical nature of the surface to be derivatised, which can be noble metal NPs [9,141,163,269,318, or metal oxides, the most commonly functionalised colloids, but also of other composition (halogenides, chalcogenides, phosphates, carbonates etc.…”

Section: Figurementioning

confidence: 99%

Functionalisation of Colloidal Transition Metal Sulphides Nanocrystals: A Fascinating and Challenging Playground for the Chemist

2017

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Abstract:Metal sulphides, and in particular transition metal sulphide colloids, are a broad, versatile and exciting class of inorganic compounds which deserve growing interest and attention ascribable to the functional properties that many of them display. With respect to their oxide homologues, however, they are characterised by noticeably different chemical, structural and hence functional features. Their potential applications span several fields, and in many of the foreseen applications (e.g., in bioimaging and related fields), the achievement of stable colloidal suspensions of metal sulphides is highly desirable or either an unavoidable requirement to be met. To this aim, robust functionalisation strategies should be devised, which however are, with respect to metal or metal oxides colloids, much more challenging. This has to be ascribed, inter alia, also to the still limited knowledge of the sulphides surface chemistry, particularly when comparing it to the better established, though multifaceted, oxide surface chemistry. A ground-breaking endeavour in this field is hence the detailed understanding of the nature of the complex surface chemistry of transition metal sulphides, which ideally requires an integrated experimental and modelling approach. In this review, an overview of the state-of-the-art on the existing examples of functionalisation of transition metal sulphides is provided, also by focusing on selected case studies, exemplifying the manifold nature of this class of binary inorganic compounds.

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“…However, n-alkane thiols are prone to fast surface reconstruction upon change of the environmental polarity or mechanical stress as can be encountered in TERS experiments with atomic force microscopy. In previous studies, we investigated the self-assembly and SAM properties of biphenyl thiols [9]. The rigid mesogen allows a defined SAM on gold and silver surfaces to be formed [10] with a superior chemical and thermal stability [11] when compared to n-alkane thiols.…”

Section: Introductionmentioning

confidence: 99%

Chemical stability of plasmon-active silver tips for tip-enhanced Raman spectroscopy

Kalbacova¹,

Rodriguez²,

Desale³

et al. 2015

Nanospectroscopy

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Silver nanostructures are used in tip- and surface-enhanced Raman spectroscopy due to their high electric field enhancement over almost the entire visible spectral range. However, the low chemical stability of silver, compared to other noble metals, promotes silver sulfide and sulfate formation which decreases its plasmonic activity. This is why silver tips are usually prepared on the same day of the experiments or are disregarded in favour of gold that is chemically more stable. Since silver degradation cannot be avoided, we hypothesized that a protection layer may be able to minimize or control degradation. In this contribution, we report the successful preparation of 4-biphenylthiol and 4’-nitro-4-biphenylthiol self-assembled monolayers on silver tips in order to protect them against tarnishing and to investigate the effect on the life-time of the plasmonic activity. The electrochemically etched wire surface was probed via Raman spectroscopy and scanning electron microscopy. The best long term stability and resistance against corrosion was shown by a monolayer of 4-biphenylthiol formed from dimethylformamide which did not display any degradation of the metallic tip during the observed period. Here, we demonstrate an easy and straightforward approach towards increasing the chemical stability of silver TERS-active probes.

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Self-assembled monolayers of rigid thiols

Cited by 83 publications

References 56 publications

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

Functionalisation of Colloidal Transition Metal Sulphides Nanocrystals: A Fascinating and Challenging Playground for the Chemist

Chemical stability of plasmon-active silver tips for tip-enhanced Raman spectroscopy

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