Self-assembled peptide nanofibers on graphene oxide as a novel nanohybrid for biomimetic mineralization of hydroxyapatite

Wang, Jinhui; Ouyang, Zhengbiao; Ren, Zhiwei; Li, Jing‐Feng; Zhang, Panpan; Wei, Gang; Su, Zhiqiang

doi:10.1016/j.carbon.2015.03.024

Cited by 117 publications

(78 citation statements)

References 51 publications

(62 reference statements)

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“…Various biologically-relevant substances/biomaterials such as DNA, blood sugar, other parameters and H 2 O 2 can be detected using Graphene and/ or its composite films [9][10][11][12][13][14][15]. We will discuss GCF based bio-sensors according to their sensing mechanism.…”

Section: Discussionmentioning

confidence: 99%

Bio-Sensing Applications of Graphene Based Composite Films

Maurya¹

2017

IJBSBE

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Graphene based composite materials have been extensively studied for the sensing applications attributing to their 2D structures, high conductivity, controlled modification and large specific surface areas, unique mechanical, optical, chemical, electrical, and catalytic properties. Therefore, a number of high quality sensors have been fabricated in recent years. Graphene based composite films (GCFs) that is base of such sensors can be prepared by combining Graphene with different functional nano-materials (carbon materials, noble metals, polymer materials, metal compounds etc.). In this review, we focus on the recent advances in bio-sensing applications of Graphene based composite films.

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Section: Discussionmentioning

confidence: 99%

Bio-Sensing Applications of Graphene Based Composite Films

Maurya¹

2017

IJBSBE

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“…Previously, various nanomaterials, such as nanoparticles [3], polymers [4,5], carbon nanotubes [6], and others [7] have been widely used for the controlled drug delivery and release. With the discovery of graphene in 2004 [8], more efforts have been spent to achieve many biomedical applications with graphene-based nanomaterials [9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in the Synthesis of Graphene-Based Nanomaterials for Controlled Drug Delivery

2017

Self Cite

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Abstract:Graphene-based nanomaterials have exhibited wide applications in nanotechnology, materials science, analytical science, and biomedical engineering due to their unique physical and chemical properties. In particular, graphene has been an excellent nanocarrier for drug delivery application because of its two-dimensional structure, large surface area, high stability, good biocompatibility, and easy surface modification. In this review, we present the recent advances in the synthesis and drug delivery application of graphene-based nanomaterials. The modification of graphene and the conjugation of graphene with other materials, such as small molecules, nanoparticles, polymers, and biomacromolecules as functional nanohybrids are introduced. In addition, the controlled drug delivery with the fabricated graphene-based nanomaterials are demonstrated in detail. It is expected that this review will guide the chemical modification of graphene for designing novel functional nanohybrids. It will also promote the potential applications of graphene-based nanomaterials in other biomedical fields, like biosensing and tissue engineering.

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“…As the irreversible nature of these covalent bonds formed in the covalent modification process would potentially hinder the electronic properties of graphene, the noncovalent modifications, by using both π-π and electrostatic interactions, offer promising ways to achieve the plane-specific functionalization of the graphene surface [21][22][23].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the formed graphene-peptide nanohybrids have shown high potentials to fabricate graphene-NPs [23,28] and graphene-hydroxyapatite [22,29] nanohybrids for various biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

Phenylalanine-Rich Peptide Mediated Binding with Graphene Oxide and Bioinspired Synthesis of Silver Nanoparticles for Electrochemical Sensing

Wang

Lin

2017

Applied Sciences

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Abstract:We demonstrated that a phenylalanine-rich peptide molecule, (FEFEFKFK) 2 , could be used for the biofunctionalization of graphene oxide (GO) and the bioinspired synthesis of silver nanoparticles (AgNPs) for the creation of functional GO-AgNPs nanohybrids. The successful synthesis of GO-AgNPs nanohybrids was proven by the characterizations of atomic force microscopy, transmission electron microscope, and X-ray photoelectron spectroscopy. The fabricated electrochemical H 2 O 2 sensor based on the synthesized GO-AgNPs nanohybrids showed high performances with a linear detection range 0.02-18 mM and a detection limit of 0.13 µM. The design of graphene-binding peptides is of benefit to the biofunctionalization of graphene-based materials, the synthesis of novel graphene-peptide nanohybrids, and the potential applications of graphene in biomedical fields.

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Self-assembled peptide nanofibers on graphene oxide as a novel nanohybrid for biomimetic mineralization of hydroxyapatite

Cited by 117 publications

References 51 publications

Bio-Sensing Applications of Graphene Based Composite Films

Bio-Sensing Applications of Graphene Based Composite Films

Recent Advances in the Synthesis of Graphene-Based Nanomaterials for Controlled Drug Delivery

Phenylalanine-Rich Peptide Mediated Binding with Graphene Oxide and Bioinspired Synthesis of Silver Nanoparticles for Electrochemical Sensing

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