Self‐Assembly and Morphology Diagrams for Solution and Bulk Materials: Experimental Aspects

Krikorian, Vahik; Kang, Youngjong; Thomas, Edwin L.

doi:10.1002/9783527631421.ch33

Cited by 3 publications

(5 citation statements)

References 155 publications

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“…Advances in the design and synthesis of well-controlled block copolymers have given rise to the rapid growth of a new class of complex nanostructures having various compositions, morphologies, sizes, and physical and biological properties − , which can serve as the primary materials for examination of the effects of nano- to microstructure size and shape on cell internalization. For example, shell-cross-linked assemblies of amphiphilic block copolymers have in recent years attracted researchers to explore their biological and medicinal uses − .…”

Section: Introductionmentioning

confidence: 99%

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

et al. 2008

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In order to probe the nanoparticle shape/size effect on cellular uptake, a spherical and two cylindrical nanoparticles, whose lengths were distinctively varied, were constructed by the selective crosslinking of amphiphilic block copolymer micelles. Herein, we demonstrate that, when the nanoparticles were functionalized with the protein transduction domain of human immunodeficiency virus type 1 Tat protein (HIV Tat PTD), the smaller, spherical nanoparticles had a higher rate of cell entry into Chinese Hamster Ovary (CHO) cells than did the larger, cylindrical nanoparticles. It was also found that nanoparticles were released after internalization, and that the rate of cell exit was dependent on both the nanoparticle shape and the amount of surface-bound PTD.

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Section: Introductionmentioning

confidence: 99%

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

et al. 2008

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“…The two main regions of the FTIR spectra that concern the hydrogen bonding of the ligand to P2VP are shown in Figure . The lower wavenumber band at 1575–1615 cm –1 are associated with the pyridine rings only. , The absorption peak at 1589 cm –1 is due to non-hydrogen bonded pyridine. Close to this band, a shoulder at 1598 cm –1 evolves upon addition of the ligand.…”

Section: Resultsmentioning

confidence: 99%

“…The lower wavenumber band at 1575−1615 cm −1 are associated with the pyridine rings only. 1,30 The absorption peak at 1589 cm −1 is due to non-hydrogen bonded pyridine. Close to this band, a shoulder at 1598 cm −1 evolves upon addition of the ligand.…”

Section: ■ Resultsmentioning

confidence: 99%

“…The continuing interest in block copolymers can be accounted for their unique capacity to form a wealth of microphase-separated morphologies, which are of potential interest for the growing field of nanotechnology . 1 For instance, block copolymer lithography enabled cost effective fabrication of devices such as flash memory, nanowire transistors, gas sensors and patterned magnetic recording media etc. For the diblock copolymers with a crystallizable block the resulting structure depends not only on the block composition and segregation strength, but also on the complex interplay between the crystallization behavior of the semicrystalline block and the glass transition of the amorphous block.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Concurrent Order in a Semi-Crystalline Diblock Copolymer Involving Complexation with a Mesogen

et al. 2013

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A semicrystalline / liquid-crystalline diblock copolymer formed by complexation of a wedge-shaped ligand, 4'-(3'',4'',5''-tris(octyloxy) benzamido) propanoic acid, with P2VP-PEO copolymer was studied. The P2VP-complex forms layers with a liquid-crystalline (LC) order causing phase segregation of the PEO block. The molar ratio ligand/pyridine (x) determines the strength of segregation between the blocks and the microphase morphology. For x ≥ 0.5, PEO forms cylinders within the LC-matrix. The phase separation strongly shifts the crystallization temperature to lower values and forces PEO to crystallize within the block copolymer cylinders. In thin films, alignment of the smectic layers parallel to the substrate induces homeotropic orientation of the PEO cylinders. Inside these cylinders, the crystalline stems preferentially orient along the smectic normal. For x ≤ 0.33, PEO forms crystalline lamellae within the LC-matrix and crystallization dominates the final structure.

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Nanoparticle directed domain orientation in thin films of asymmetric block copolymers

et al. 2014

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Self‐Assembly and Morphology Diagrams for Solution and Bulk Materials: Experimental Aspects

Cited by 3 publications

References 155 publications

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake

Concurrent Order in a Semi-Crystalline Diblock Copolymer Involving Complexation with a Mesogen

Nanoparticle directed domain orientation in thin films of asymmetric block copolymers

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