“…Vesicles play vital roles in cell functions, such as transport and storage of materials, 1 metabolism, 2 cell communication, 3 etc. Inspired by nature, an ocean of artificial vesicles have been constructed from amphiphilic polymers, 4,5 various amphiphiles, [6][7][8] supramolecular amphiphiles, 5,[9][10][11][12][13] and even nonamphiphilic structures 14,15 in the past decades, and they have shown great potential applications in biomimetics, 16 nanomaterials, 17 drugs, and gene delivery. 18,19 Size is an important factor for vesicles, which is related to their properties and functions, such as distribution and loading.…”