Self-assembly of high-nuclearity lanthanide-based nanoclusters for potential bioimaging applications

Abstract

Two series of Cd-Ln and Ni-Ln clusters [Ln8Cd24L12(OAc)44(48)Cl4(0)] and [Ln8Ni6L6(OAc)24(EtOH)6(H2O)2] were constructed using a flexible ligand. The Cd-Ln clusters exhibit interesting nano-drum-like structures which allows direct visualization by TEM. Luminex MicroPlex Microspheres loaded with the Cd-Sm cluster were visualized using epifluorescence microscopy. Cytotoxicity studies on A549 and AGS cancer cell lines showed that the materials have mild to moderate cytotoxicity.

The Role of Blue‐Emissive 1,8‐Naphthalimidopyridine N‐Oxide in Sensitizing EuIII Photoluminescence in Dimeric Hexafluoroacetylacetonate Complexes

“…In the past two decades, luminescent organic lanthanide complexes have not only shown extensive applications in light‐converting and optoelectronic materials, but they have also shown more attractive prospects in bioanalytical areas, such as fluoroimmunoassay, analytical sensors, and bioimaging The synthesis of materials with high luminescence quantum yields is the premise for their practical applications. Among the reported complexes, lanthanide β‐diketonates are among the most highly investigated luminescent rare‐earth coordination compounds, because of their high chemical stability, easy preparation, and bright emission .…”

A self-assembling luminescent lanthanide molecular nanoparticle with potential for live cell imaging

“… 17 Typically, the (CH 2 ) n chain lengths of the ligands can affect the structures of the d–f clusters. 18 In this work we report the use of three chain-like Schiff base ligands, H 2 L 1–3 ( Scheme 1 ), which have flexible carbon–carbon backbones containing 5, 6 and 10 methylene units, respectively. Reactions of H 2 L 1–3 with Cd(OAc) 2 ·4H 2 O and Ln(OAc) 3 ·4H 2 O resulted in three 32-metal Cd–Tb nanodrum-like clusters, [Tb 8 Cd 24 (L 1 ) 12 (OAc) 48 ] ( 1 ), [Tb 8 Cd 24 (L 2 ) 12 (OAc) 48 ] ( 2 ) and [Tb 8 Cd 24 (L 3 ) 12 (OAc) 48 ] ( 3 ).…”

Structures and luminescent sensors of mixed‐counterions based salen‐type lanthanide coordination polymers

“…Although certain co‐relationship among structure, the radii of lanthanide, and lanthanide counterion has been investigated, the co‐relationship between the structures and the mixed lanthanide counterions remains challenging. Additionally, photoluminescence (PL) of salen‐type lanthanide complexes has been extensively investigated . Luminescence of lanthanide ions in complexes is sensitive to coordination environment, that providing a platform for sensing anions, cations and even small organic molecules .…”