COVID-19, apart from its profound health impact, has significantly modified the way people view life, from facing this limiting reality of the patient who can debate between life and death, to variable realities of those who do not suffer from it. or especially, of those who contribute to the healing processes by providing their accompaniment. The research is of a correlational type, based on evaluating the relationship between psychological well-being and coping strategies in positive COVID-19 patients, carried out from May to October 2021. It was carried out at the Huaycán hospital, taking an intentional sample of 104 COVID-19 positive patients. Nursing staff were previously instructed in psycho-emotional support techniques, as well as biosafety techniques, and received bimonthly psychological support. It was concluded that the support of the nursing staff contributed to the development of effective coping styles and strategies for the remission of the disease, but this, in turn, was significantly contributed by the training process and psychological support received by the nurses. , in whom this support substantially improved their mental health, after the completion of the investigation.